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Clascoterone CAS:19608-29-8 Umukozi Ukora
Clascoterone ni umuti ugabanya androgen receptor urimo gukorwa nk'amavuta yo mu bwoko bwa cream n'umuti utangwa na Cassiopea (ikigo cy’ubucuruzi cya Cosmo Pharmaceuticals) mu kuvura indwara z'uruhu ziterwa na androgen, harimo alopecia ya androgenetic na acne vulgaris. Nubwo uburyo nyabwo bwo kuvura acne vulgaris butazwi, uyu muti uzwiho guhangana na androgen dihydrotestosterone mu gufatana na androgen receptors mu ngirabuzimafatizo z'umusatsi no mu dusatsi kugira ngo ugabanye ibimenyetso bikenewe kugira ngo acne itere imbere.
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Pitavastatin CAS:147511-69-1 Umukozi Ukora
Pitavastatin ni umuti ubuza HMG-CoA reductase itera intambwe ya mbere yo gukora cholesterol. Igaragara nk'ifu idafite impumuro kandi y'umweru ikavamo umuhondo werurutse. Igira ingaruka nziza mu kugabanya urugero rw'ibinure bimwe na bimwe nka cholesterol mu mubiri. Kubwibyo, ikoreshwa cyane cyane mu kuvura hypercholesterolaemia no gukumira indwara z'umutima n'imitsi. Ntabwo igabanya gusa cholesterol nyinshi na triglyceride ku barwayi bamwe na bamwe, ahubwo ishobora no kongera ingano ya lipoprotein nyinshi (HDL), urugero rwa cholesterol "nziza". Muri rusange igomba gutangwa hamwe n'indyo ikwiye.
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Teduglutide CAS:197922-42-2 Umukozi Ukora
Teduglutide (izwi kandi nka ALX-0600) ni ubwoko bwa GLP-2 aho glycine yasimbuwe na alanine ku mwanya wa 2 uvuye kuri N-terminus, bityo igatanga ubudahangarwa bwo kwangirika na DPP-4. Teduglutide ifite ubushobozi bwo gufatanya, imbaraga za agonist, n'ubushobozi bwa agonist nk'ubwa GLP-2 mu isuzuma hamwe na receptor ya GLP-2 y'imbeba. Gutanga teduglutide ku mbeba byatumye ibiro by'amara mato byiyongera cyane ndetse binatuma uburebure bwa villi y'amara bwiyongera. Teduglutide yateguwe hakoreshejwe peptide ikora mu buryo bwa solid-phase.
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Aside ya Malic CAS: 6915-15-7 Umukozi Ukora
Aside ya Malike ni aside 2-hydroxydicarboxylic ari yo aside succinic aho imwe muri hydrogens ifatanye na karuboni isimburwa n'itsinda rya hydroxy. Ifite uruhare mu kugenzura aside mu biribwa no mu buryo bw'ibanze bwa metabolite. Ni aside 2-hydroxydicarboxylic na aside C4-dicarboxylic. Ikomoka kuri aside succinic. Ni aside conjugate ya malate (2-) na malate.
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Gabapentin CAS: 60142-96-3 Umukozi Ukora
Gabapentin ni umusemburo ukomeye ubuza iyi ndwara, ukora ukoresheje uburyo bwa GABA receptors ziherereye mu mugongo. Gabapentin ni aside γ-aminobutyric (GABA) ikora nk'umuti ugabanya ububabare bw'imitsi, ikaba ifite ingaruka nziza ku burwayi mu ndwara zitandukanye z'imitsi nka Complex Regional Pain Syndrome type one (CRPS 1).
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Parasetamol CAS: 103-90-2 Umukozi Ukora
Parasetamol ni kimwe mu bigize ubwoko bwa phenols ari byo 4-aminophenol aho imwe muri hydrogens ifatanye n'itsinda ry'amine yasimbuwe n'itsinda rya acetyl. Ifite uruhare nk'umuti ubuza cyclooxygenase 2, umuti ubuza cyclooxygenase 1, umuti ugabanya ububabare utari uwo mu biyobyabwenge, umuti urwanya indwara zo mu bwonko, umuti ubuza ububyimbirwe utari uwo mu bwoko bwa steroide, umuti ubuza cyclooxygenase 3, umuti ubuza xenobiotic, umuti uhumanya ibidukikije, umuti utuma amaraso y'umuntu ahinduka mu maraso, umuti uhumanya umwijima, umuti utera ferroptosis n'umuti urinda geroprotector. Ni kimwe mu bigize phenols kandi ni kimwe mu bigize acetamides. Ifitanye isano n'imikorere ya 4-aminophenol.
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Kalisiyumu ya Aspartate CAS: 10389-09-0 Umukozi Ukora
Kalisiyumu ya Aspartateni imwe mu myunyu ngugu iboneka cyane mu mubiri kandi ni ingenzi mu buzima bwacu. Iyo tutayifite, abantu ntibashobora gukomeza amagufwa n'amenyo. Hafi 99% bya kalisiyumu mu mubiri iba iri muri ibi bice bibiri. Byongeye kandi, kalisiyumu ifasha umutima, imitsi, imitsi n'izindi gahunda z'umubiri gukora neza. Ifite imiterere ihamye ya shimi, ishonga neza mu mazi kandi ikagira umuvuduko mwinshi wo kwinjiza. Ni mu itsinda riheruka rya kalisiyumu ikomeza intungamubiri.
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L-Carnitine L-Tartrate CAS: 36687-82-8 Umukozi Ukora
L-carnitine ni aside amine ikomoka ku bimera karemano ikoreshwa nk'inyongera mu kugabanya ibiro. L-carnitine-L-tartrate (LCLT) ni umunyu wa L-carnitine urimo aside tartaric. LCLT ifite ubushobozi bwo kurinda imiti no kurwanya udukoko..
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Miconazole CAS: 22916-47-8 Umukozi Ukora
Miconazole (Monistat) ni umuti urwanya icyorezo wa imidazole ukoreshwa mu kuvura indwara zo mu ruhu n'uturemangingo tw'imitsi. Indwara za Candida, nka vaginitis, zifata uruhu cyane. Hari uruhu cyangwa uturemangingo duto cyane. Hari ububabare buke ku ruhu no mu turemangingo tw'imitsi. Hari ibimenyetso byerekana ko hari ububabare bw'uruhu n'uturemangingo tw'imitsi mu gihe umuntu akoresha imiti yo mu ruhu; hari ibimenyetso byerekana ko hari ububabare mu nda, kubabara umutwe, ndetse no kubabara mu nda mu gihe umuntu akoresha imiti yo mu ruhu.
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Umunyu wa Pyrroloquinoline Quinone Disodium CAS:122628-50-6
Umunyu wa disodium wa Pyrroloquinoline quinone ni ikinyabutabire cya quinone gishongera mu mazi gifite ubushobozi bukomeye bwo kurwanya antioxidant. Iki gicuruzwa ni ifu y'umutuku wijimye. Cyakuwe mu miterere ya bagiteri za methylotrophic n'uturemangingo tw'inyamabere. Iyi ntungamubiri y'ingenzi ni ingenzi ku nyamabere, igira uruhare runini mu kongera imikorere y'ubudahangarwa bw'umubiri.
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Umukozi wa Citrulline CAS: 372-75-8
Citrulline ni L-enantiomeri ya citrulline. Ifite uruhare nk'umurinzi wa EC 1.14.13.39 (nitric oxide synthase), irinda, ikora intungamubiri, ikora intungamubiri nto, ikora umubiri w'umuntu, Escherichia coli metabolite, Saccharomyces cerevisiae metabolite na metabolite y'imbeba. Ni enantiomeri ya D-citrulline. Ni tautomer ya L-citrulline zwitterion.
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L-Arginine Alpha-Ketoglutarate (2: 1) Dihydrate CAS: 5256-76-8
L-Arginine Alpha-Ketoglutarate (2: 1) Dihydrateni umuti ukomoka ku miti uri mu itsinda ry'imiti ikoreshwa mu kuvura hyperlipidemie. Imiterere y'uyu muti igizwe na molekile ebyiri za arginine zihujwe na atome ya ogisijeni. Ni ikintu cy'agaciro gakomeye gifite umurambararo w'uduce duto wa 0.3 μm n'ingano y'uduce iri hagati ya 0.05 na 1.5 μm.
