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Umukozi ushinzwe gukora Hydrocortisone Base CAS: 50-23-7
Hydrocortisone, 11β, 17,21-trihydroxypregn-4-ene-3,20-dione, ni yo GCin y’ibanze mu bantu karemano. Nubwo hari umubare munini wa GCs zikozwe mu buryo bwa sintetike, hydrocortisone, esters zayo, n'umunyu wayo biracyari ingenzi mu buvuzi bwa steroid bugezweho bwa adrenocortical ndetse n'urugero rwo kugereranya izindi GC na MC zose. Ikoreshwa mu bimenyetso byose byavuzwe haruguru.
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Orlistat CAS: 96829-58-2 Umukozi Ukora
Orlistat ni umuti ubuza lipase mu igogora. Orlistat yatangijwe mu Bwongereza nka Xenical mu kuvura umubyibuho ukabije igihe kirekire, byaba byiza ifatanyije n'indyo ifite karori nke. Orlistat ni umuti ukomoka kuri tetrahydro-derivative wa lipstatin karemano ya hypolipidemic (ikomoka kuri Streptomyces toxyfncini) kandi ishobora kuboneka binyuze muri hydrogenation ya lipstatine cyangwa hakoreshejwe uburyo butandukanye bwo gukora bukoresha intambwe nyinshi kuva kuri (S) - aside rnalic.
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L-Homoarginine Monohydrochloride CAS: 1483-01-8 Umukozi Ukora
L-Homoarginine ni umuti udahiganwa kandi ugabanya uburemere bwa phosphatase za alkaline mu ngingo. Iyi aside amine idakenewe ibuza phosphatase za alkaline mu magufwa no mu mwijima ariko nta ngaruka igira ku misemburo ya placenta cyangwa amara. Kuvura L-homoarginine mbere yo kuyivura bitinda mu mikurire y'ikibyimba mu buryo bwa C3H/He osteosarcoma. Ibuza kandi gukura kwa poroteyine nyinshi mu mirire y'imbeba no gusohora enzymes mu mbeba zikomoka ku mitobe ya nyongo, urugero rwo gutuma enzymes za pancreatic zisohoka hamwe n'umutobe wa hypercholecystokininemia..
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Escitalopram Oxalate CAS:219861-08-2
Escitalopram oxalate ni metabolite ya S-isomer ya citalopram ikaba ari nayo igize uruhare runini mu mikorere yayo mu buvuzi. Izina ryayo ry’ibinyabutabire ni (S) -1- [3- (dimethylamino) propyl] -1- (Chemicalbook4-fluorophenyl) -1,3-dihydroisobenzofuran 5-acetonitrile oxalate, Ni igabanya serotonin igabanya ubukana, Igira ingaruka nziza ku ndwara zo kwiheba haba mu mubiri no mu mubiri.
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Glutathione yagabanutse CAS: 70-18-8 Umukozi Ukora
Glutathione (GSH) ni tripeptide (γ-glutamylcysteinylglycine) ikwirakwizwa cyane mu bimera no mu nyamaswa. GSH ikora nk'igice cy'ingenzi cya glutathione transferases mu gukuraho xenobiotics kandi ni ingenzi mu gutanga electron kuri glutathione peroxidases mu kugabanya hydroperoxides. GSH kandi igira uruhare mu gutwara aside amine no kubungabunga poroteyine sulfhydryl igabanuka. Ingano ya GSH iri hagati ya mikoromolari nke muri plasma na milimolari nyinshi mu turemangingo nk'umwijima.
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Cysteine CAS: 52-90-4 Umukozi Ukora
L-Cysteine ni imwe muri aside amine 20 karemano, kandi uretse methionine, ni yo yonyine irimo sulfur. Ni aside amine idafite akamaro ka thiol ishyirwamo oxidation kugira ngo ikore Cystine. Ni aside amine idafite akamaro ka sulfure mu bantu, ifitanye isano na cystine, Cysteine ni ingenzi mu gukora poroteyine, gusohora uburozi, no gukora imikorere itandukanye ya metabolic. Iboneka muri beta-keratin, poroteyine y'ingenzi mu nzara, uruhu, n'umusatsi, Cysteine ni ingenzi mu gukora kolajeni, ndetse no gutuma uruhu rukomera kandi rukagira imiterere myiza.
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Aside yigenga ya Coenzyme A CAS: 85-61-0
aside y'ubuntu ya Coenzyme Ani cofactor y'ingenzi ikora nk'itsinda ritwara aside na carbonyl rikora ku mikorere ya aside citric na metabolism ya aside kirisi. Hafi 4% bya enzymes zo mu turemangingo zikoresha CoA nk'umubumbe. Ikorwa muri aside pantothenic mu ntambwe 5 zikenera ATP. Intambwe ya pantothenate kinase y'inzira ya CoA biosynthetic yagaragaye ko ari yo ntego yo guteza imbere imiti irwanya bagiteri.
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Idebenone CAS: 58186-27-9 Umukozi Ukora
Idebenone ni ikintu kigizwe n'ibinyabuzima biri mu muryango wa quinone, kikaba gisa na coenzyme Q-10. Ni ubwoko bw'umuti wakozwe na Takeda Pharmaceutical Company mu kuvura indwara ya Alzheimer n'izindi ndwara zimwe na zimwe zo mu mutwe. Ariko, ibi ntabwo byateye imbere cyane kuri iki kimenyetso. Ubu ikoreshwa no mu kuvura indwara ya Friedreich's ataxia, ikaba igira ingaruka nziza ku ndwara y'umutima iterwa no kugabanuka k'amaraso mu bwonko no ku mikorere y'imitsi.
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Tetracaine Hydrochloride CAS: 136-47-0 Umukozi Utanga
Tetracaine hydrochloride ni ester ya benzoate. Ni umuti ukomeye wo mu gace k'umubiri wo mu bwoko bwa ester ukoreshwa mu gutera ikinya ku buso no mu ruti rw'umugongo. Tetracaine hydrochloride ni umuti utera ikinya ku gace k'umubiri kandi ukaba ukomoka kuri aside p-amino benzoic. Ukora mu kubangamira uburyo iyoni za sodium zinjira mu turemangingo tw'imitsi kandi ni umwe mu miti ikunze gukoreshwa mu gutera ikinya ku mubiri.
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Leucine CAS: 61-90-5 Umukozi Ukora
Leucine ni imwe muri aside amine umunani z'ingenzi, kandi igize aside amine aliphatic iri mu bwoko makumyabiri bwa poroteyine. L-leucine na L-isoleucine na L-valine byitwa aside amine eshatu zifite amashami. L-leucine Leucine na D-leucine ni enantiomers. Ni kristu yera irabagirana ya hexahedral cyangwa ifu y'umweru ya kristu ku bushyuhe bw'icyumba, nta mpumuro, isharira gato. Iyo hari hydrocarbons, iba ihamye muri aside mineral y'amazi. Kuri garama imwe ishongeshwa mu mazi ya mililitiro 40 na aside asetiki ya mililitiro 100. Ishongeshwa gato muri ethanol cyangwa ether, ishongeshwa muri aside formic, ishongeshwa muri aside hydrochloric, ifu y'alkali hidroxide n'ifu ya karubone.
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Aside ya Guanidinopropiyoni CAS: 353-09-3 Umukozi Ukora
Aside Guanidinopropionic ni kristu yera ishongera mu mazi kandi ikaba ari creatine analog. Aside Guanidinopropionic ni ubwoko bw'ibikomoka kuri aside amine. Ni igikoresho cy'ingenzi cya shimi kandi kiri hagati. Kiba mu maraso, mu bwonko, mu mwijima, mu mpyiko no mu nkari z'inyamabere.
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Olmesartan CAS: 144689-24-7 Umukozi Ukora
Olmesartan medoxomil,phenyl]phenyl]methyl]imidazole-4-carboxylate (Benicar, Olmetec) ikoresha sisitemu ya tetrazolering nk'uburyo bwayo butuma aside ifatana. Iyo ihawe umurwayi, uyu muti utangira gukora vuba kandi neza binyuze mu gushonga kwa ester ya medoxomil mu gihe cyo kwinjiza mu gifu. Olmesartan ni biphenylyltetrazole. Ifite uruhare mu kugabanya umuvuduko w'amaraso n'uburyo bwo kurwanya angiotensin receptor antagonist.
