Boc-MeIle-OH CAS: 52498-32-5

Boc-MeIle-OH ikoreshwa cyane mu gukora peptide ikoze mu cyiciro gikomeye kugira ngo hakorwe peptide zakozwe ku giti cyazo zifite uruhererekane n'imikorere yihariye. Nk'uburyo burinzwe bwa N-methyl-isoleucine, yemerera kwinjiza ibisigazwa bya N-methyl-isoleucine mu ruhererekane rwa peptide rurimo gukura, bikarinda ingaruka mbi zitifuzwa kandi bigatuma peptide zikomeye zikora neza zifite imiterere yihariye. Mu bijyanye no guhuza ibinyabuzima n'ibinyabuzima, Boc-MeIle-OH ikora nk'inkingi ikomeye yo gukora peptide zikora neza, imashini zigaragaza ibirango, n'imiti ishingiye kuri peptide. Ikoreshwa ryayo ryemerera guhindura neza peptide na poroteyine, byorohereza iterambere rya molekile zikora neza zifite ubushobozi bwo guhagarara neza, ubushobozi bwo gushushanya, cyangwa ubushobozi bwo gufata amashusho mu buryo butandukanye bwa biomedical. Byongeye kandi, mu kuvumbura imiti no guteza imbere ubuvuzi, Boc-MeIle-OH ikoreshwa mu gukora peptide conjugates na peptides zahinduwe zifite imiterere myiza ya pharmacokinetic n'ibikorwa bya biyoloji. Izi mpinduka zishobora kongera imikorere, guhitamo, no gutanga imiti ishingiye kuri peptide, bigatanga umusanzu mu iterambere ry'ubuvuzi bunoze n'imiti igamije kuvura. Muri rusange, ubwizerwe bwa Boc-MeIle-OH mu gukora peptide no guhuza ibinyabuzima bituma iba igikoresho cy'ingenzi mu guteza imbere ubushakashatsi mu kuvumbura imiti, ibinyabuzima by'ibinyabutabire, na proteomics, bitanga amahirwe atandukanye yo guteza imbere uburyo bushya bwo gukoresha imiti.