N-methyl-2,2,2-trifluoroacetamide CAS:815-06-5

N-Methyl-2,2,2-trifluoroacetamide (NMTFA) irangwa n'imiterere yayo ya molekile, irimo itsinda rya trifluoromethyl (-CF3) rifatanye n'umugongo wa acetamide (-CONHCH3). Iyi miterere itanga ituze n'imikorere ikomeye kuri NMTFA, bigatuma ikoreshwa mu buryo butandukanye bw'imiti. NMTFA isanzwe ibaho nk'ikintu gikomeye gifite aho gishongesha hafi 62°C kandi igaragaza ubushobozi bwo gushonga neza mu bintu bishongesha ibinyabuzima nka acetone na ethanol. Gukomera kwayo mu bihe bitandukanye bituma ikoreshwa neza mu bushakashatsi bwa laboratwari no mu nganda. Ikoreshwa rya Organic Synthesis: NMTFA ikora nk'igice cy'ingenzi mu guhuza ibinyabuzima, cyane cyane mu kwinjiza amatsinda ya trifluoromethyl mu bintu bito. Ubu bushobozi ni ingenzi mu guteza imbere imiti, imiti ikomoka ku buhinzi, n'imiti yihariye ifite imikorere myiza ya biyolojiya n'ubudahangarwa bwa shimi. Ubuhanga mu by'imiti: Mu mikoreshereze y'imiti, NMTFA ikoreshwa nk'intangiriro mu guhuza ibintu bikomoka ku miti (API) bitewe n'ubushobozi bwayo bwo gutanga imiterere myiza y'imiti. Igira uruhare runini mu buvuzi bw’imiti binyuze mu gutuma habaho impinduka mu miterere y’imiti kugira ngo yongere imikorere no kugabanya ubushobozi bwo kwangirika kw’imiti. Imiti yihariye: NMTFA ikoreshwa mu gukora imiti yihariye nka surfactants, plasticizers, n’ibindi bintu bito bikoreshwa mu gukora imiti ikomoka ku buhinzi n’imiti myiza. Uburyo ikora mu guhindura imiti butuma igira akamaro mu miterere aho igenzura neza imiterere n’imikorere ya molekile bikenewe. Guhuza N-Methyl-2,2,2-trifluoroacetamide bikorwa binyuze mu gukora aside trifluoroacetic hamwe na methylamine. Iyi nzira ikubiyemo guhuzwa kwa aside trifluoroacetic hamwe na methylamine mu buryo bugenzurwa kugira ngo habeho NMTFA. Ubusanzwe iyo habayeho catalyst ikwiye kugira ngo yorohereze ishingwa ry’imiti. Uburyo bwo gutunganya nka recrystallization cyangwa chromatography bukoreshwa kugira ngo NMTFA ibe nziza cyane ikwiriye gukoreshwa mu nganda. Uburyo bworoshye bwo gukora no kuboneka kw'ibikoresho fatizo bigira uruhare mu gutuma ihendutse kandi ikoreshwe cyane mu bushakashatsi bw’ubushakashatsi n’inganda. Muri make, N-methyl-2,2,2-trifluoroacetamide ni ikintu gifite akamaro kanini mu gukora imvange y’ibinyabuzima, mu buhanga mu by’imiti, no mu gukora imiti yihariye. Imiterere yacyo yihariye y’ibinyabutabire, harimo gutuza, gukora neza, no koroshya imvange, bigira uruhare mu guteza imbere ikoranabuhanga mu nzego zitandukanye z’inganda n’amasomo ya siyansi.