N-methyl-2,2,2-trifluoroacetamide CAS:815-06-5

N-Ethyl 2-methyl-4,4,4-trifluoroacetoacetate (EMTFA) irangwa n'imiterere yayo ya molekile, irimo itsinda rya trifluoromethyl (-CF3) rifatanye n'umugongo wa β-keto ester. Iyi miterere itanga ituze n'imikorere ikomeye kuri EMTFA, bigatuma ikoreshwa mu buryo butandukanye bwa shimi. EMTFA isanzwe ibaho nk'amazi asobanutse neza, adafite ibara afite ubushyuhe bugera kuri 140°C kandi igaragaza ubushobozi bwo gushonga neza mu bintu bisanzwe bya organic nka acetone na ethyl acetate. Gukomera kwayo mu bihe bitandukanye bituma ikoreshwa neza mu bushakashatsi bwa laboratwari no mu nganda. Ikoreshwa rya Organic Synthesis: EMTFA ikora nk'inkingi y'ingenzi mu gukora organic synthesis, cyane cyane mu gushyiramo trifluoromethylated motifs muri organic molecules. Ubu bushobozi ni ingenzi mu guteza imbere imiti, agrochemicals, n'ibindi binyabutabire byihariye bifite imikorere myiza ya biology hamwe no kudahinduka kwa shimi. Pharmaceutical Chemistry: Mu gukoresha imiti, EMTFA ikoreshwa nk'intangiriro mu gukora ibintu bikora imiti (APIs) bitewe n'ubushobozi bwayo bwo gutanga imiterere myiza ya pharmacological. Igira uruhare runini mu buvuzi bw’imiti binyuze mu gutuma habaho impinduka mu miterere y’imiti kugira ngo yongere imikorere no kugabanya ubushobozi bwo kwangirika kw’imitsi. Imiti yihariye: EMTFA ikoreshwa mu gukora imiti yihariye nk’imiti yica udukoko, imiti yica udukoko, n’ibindi bintu bito bikoreshwa mu gukora imiti ikomoka ku buhinzi n’imiti myiza. Uburyo ikora mu guhindura imiti butuma igira akamaro mu miterere aho igenzura neza imiterere n’imikorere ya molekile bikenewe. Gutunganya Ethyl 2-methyl-4,4,4-trifluoroacetoacetate bikorwa binyuze mu nzira y’intambwe nyinshi uhereye kuri Claisen condensation reaction ya ethyl trifluoroacetate hamwe na methyl acetate, hagakurikiraho esterification mu bihe bigenzurwa. Ubusanzwe iyi reaction ikorwa iyo hari catalyst y’ibanze kugira ngo yorohereze β-keto ester. Uburyo bwo gutunganya nka distillation cyangwa recrystallization bukoreshwa kugira ngo EMTFA ibe nziza cyane ikwiriye gukoreshwa mu nganda. Uburyo bworoshye bwo gukora no kuboneka kw’ibikoresho byo gutangiza bigira uruhare mu gutuma ihendutse kandi ikoreshwe cyane mu bushakashatsi bw’ubushakashatsi n’inganda. Muri make, ethyl 2-methyl-4,4,4-trifluoroacetoacetate ni ikintu gifite akamaro kanini mu gukora imvange y’ibinyabuzima, mu buhanga mu by’imiti, no mu gukora imiti yihariye. Imiterere yacyo yihariye y’ibinyabutabire, harimo gutuza, gukora neza, no koroshya imvange, ibishyira mu mwanya w’ingenzi mu guteza imbere ikoranabuhanga mu nzego zitandukanye z’inganda n’amasomo ya siyansi.