Vitamine B7 (Vitamine H/D-Biotin) CAS: 58-85-5 Umukozi Ukora

Biotin ni ngombwa mu gukura kw'uturemangingo, gukora aside irike, no gukora neza kw'ibinure na aside amine. Igira uruhare mu mikorere ya aside citric, ari na yo nzira ingufu za biochemical zikorwamo mu gihe cyo guhumeka. Biotin ni coenzyme ya enzymes za carboxylase, igira uruhare mu gukora aside irike, isoleucine, na valine, no muri gluconeogenesis. Nk'itsinda rya coenzyme ya phthalocyanine coenzyme A, Biotin igira uruhare mu gukora aside irike, igatuma habaho glycine CoA. Iyi reaction ni intambwe ya mbere mu gukora aside irike, hanyuma binyuze muri cytoplasmic multi-enzyme complex na fatty acid synthase ikora aside palmitic iva kuri phthalocyanine-CoA. Mu kongerera igihe uruhererekane rwa karuboni muri aside irike, propanedio phthalide-ACP igira uruhare mu gukora reaction nk'umutanga wa dicarboni, naho dipropyl phthalide-ACP ikomoka kuri phthalide-CoA. Bigaragara ko biotin ari ngombwa mu gukora aside irike no kwagura uruhererekane rwa karuboni muri aside irike. Kubura biotin bishobora gutera imikorere mibi y’ibinure mu mubiri, bigatera impinduka mu miterere y’aside irike mu mubiri.