Trt-Gly-OH CAS: 5893-05-0

Bz-His-OMe igira uruhare runini mu gukora peptide, ikaba inkingi y'ingenzi mu kubaka peptide zifite imiterere yihariye n'imikorere. Itsinda ririnda benzyl rigenzura ko ibisigazwa bya histidine bitahinduka mu gihe cyo gukora peptide, bigatuma peptide iterana neza kandi igenzurwa. Byongeye kandi, kuba hari itsinda rya methyl ester bigira ingaruka ku buryo peptide ikora neza ndetse no ku mikoranire yayo, bigatuma igira akamaro mu gukora peptide zifite ubushobozi bwo kongera ubushobozi bwo kwinjira mu ruhu cyangwa ubushobozi bwihariye bwo kwibandaho. Mu guteza imbere imiti, iyi mvange ishobora gukoreshwa mu gukora imiti ishingiye kuri peptide ifite ubushobozi bwo guhagarara neza no kuba iboneka neza, bishobora gutuma habaho imikorere myiza mu kuvura. Uretse uruhare rwayo mu gukora peptide, Bz-His-OMe ikoreshwa mu bushakashatsi bwa poroteyine n'ubushakashatsi bwa biochemical, aho ishobora gukoreshwa mu kwiga imikoranire ya poroteyine na poroteyine, gukora ubushakashatsi ku bikorwa bya enzyme, no gusuzuma impinduka zishingiye kuri pH muri poroteyine. Imiterere yayo ijyanye n'imiterere ye ituma abashakashatsi bashobora gusuzuma uburyohe bw'imikorere y'uturemangingo n'uburyo indwara zigenda, bigira uruhare mu iterambere mu gusobanukirwa ubuzima n'indwara. Uburyo iyi mvange ikora neza kandi ihuye n’imiterere itandukanye y’igerageza bituma iba ingenzi cyane mu gusesengura ingorane z’imikorere y’ibinyabuzima no guteza imbere uburyo bwo kuvura indwara zitandukanye. Muri make, Bz-His-OMe ni igikoresho cy’agaciro ku bashakashatsi mu bijyanye no gukora peptide, guteza imbere imiti, n’ubushakashatsi ku binyabuzima, itanga ubushobozi bwo guhindura peptide zifite imiterere yihariye no gusesengura uburyo bw’ibanze bw’imikorere y’ibinyabuzima, bityo ikagira uruhare mu iterambere mu buvuzi no mu ikoranabuhanga.