H-Gly-OBzl·Tos CAS:1738-76-7

H-Gly-OBzl·Tos igira uruhare runini mu gukora peptide, ikaba inkingi y'ingenzi mu kubaka peptide zifite imiterere yihariye n'imikorere. Itsinda rya benzyl ester n'itsinda ririnda tosyl bigenzura ko ibisigazwa bya glycine bitahinduka mu gihe cyo gukora peptide, bigatuma peptide iteranywa neza kandi ikagenzurwa. Iki kinyabutabire ni ingenzi mu gushushanya peptide zifite imiterere yihariye nko kunoza uburyo zihagarara, kuba ziboneka neza, cyangwa kurwanya kwangirika kwa enzyme, bigatuma kiba igikoresho cy'ingenzi mu iterambere ry'imiti, cyane cyane mu gukora imiti ishingiye kuri peptide. Uretse uruhare rwayo mu gukora peptide, H-Gly-OBzl·Tos isanga ikoreshwa mu bushakashatsi bwa proteinomike n'ubuhanga bwa biochemical, aho ishobora gukoreshwa mu kwiga imikoranire ya protein na protein, gukora ubushakashatsi ku mikorere ya enzyme, no gusuzuma imikorere ya proteine. Imiterere yayo ijyanye n'imiterere ye ituma abashakashatsi bashobora gusuzuma uburyohe bw'imikorere y'uturemangingo n'imikorere y'indwara, bigira uruhare mu iterambere mu gusobanukirwa ubuzima n'indwara. Uburyo iki kinyabutabire gihura n'imiterere itandukanye y'igerageza bituma kiba ingenzi mu gusesengura ingorane za sisitemu za biyoloji no guteza imbere uburyo bwo kuvura indwara zitandukanye. Muri make, H-Gly-OBzl·Tos ni igikoresho cy'agaciro ku bashakashatsi mu bijyanye no gukora peptide, guteza imbere imiti, n'ubushakashatsi ku binyabuzima, itanga ubushobozi bwo guhindura peptide zifite imiterere yihariye no gusesengura uburyo bw'ibanze bw'imikorere y'ibinyabuzima, bityo igatanga umusanzu mu iterambere mu buvuzi no mu ikoranabuhanga.