TOPS CAS:40567-80-4 Igiciro cy'umukozi

Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate, izwi kandi ku izina rya MESNa, ifite ingaruka n'ikoreshwa ryihariye muri biochimie na molekile. Ikoreshwa cyane cyane nk'ikintu kigabanya ubukana bw'amatsinda ya thiol (-SH) muri poroteyine na peptides.

MESna ikora nk'ikintu gikomeye kigabanya ibintu, gishobora guhindura imigozi ya disulfide (-SS-) muri poroteyine ikayihinduramo amatsinda ya sulfhydryl (-SH). Iyi nzira yo kugabanya ibintu ni ingenzi mu bikorwa bitandukanye bya siyansi, harimo gusesengura poroteyine, kuyisukura no kuyitunganya.

Zimwe mu ngamba zihariye za MESna zirimo:

Guhindura poroteyine: MESNa ishobora gukoreshwa mu guhindura poroteyine binyuze mu guca imigozi ya disulfide, bityo ikagaragaza imiterere ya poroteyine no koroshya isesengura cyangwa gutunganya poroteyine.

Kugabanya Kwishyira hamwe kwa Poroteyine: MESNa ishobora gukumira kwishyira hamwe kwa poroteyine igabanya imigozi ya disulfide, ikarinda poroteyine guhagarara neza no gushonga mu gisubizo.

Ibirango bya Poroteyine: MESNa ishobora gukoreshwa mu gushyiramo ibirango cyangwa impinduka ku bisigazwa bya cysteine ​​muri poroteyine binyuze mu guca imigozi ya disulfide no gushyira ahagaragara amatsinda ya sulfhydryl (-SH).

Gusubiramo Poroteyine: MESNa ikoreshwa mu gufasha poroteyine gusubiramo nyuma yo guhindagurika mu kugabanya imigozi ya disulfide no gufasha mu ikorwa ryiza ry’imiterere ya poroteyine.