Kalisiyumu ya Rosuvastatin CAS: 147098-20-2 Utanga ibicuruzwa

Kalisiyumu ya Rosuvastatin ni inhibitori ya HMG-CoA reductase.HMG-CoA reductase inhibitor ni enzyme igabanya igipimo cya hydroxy-3-methylglutaryl coenzyme A kugirango ihindure A (Ibibanziriza cholesterol).Ikibanza nyamukuru cyibikorwa bya rosuvastatin ni umwijima-ingingo zigenewe cholesterol-igabanya.Rosuvastatin yongera umubare wa reseptor ya LDL yakira hejuru ya selile, igatera kwinjiza na catabolisme ya LDL, ikabuza synthesis ya hepatike ya VLDL, bityo bikagabanya umubare rusange w’ibice bya VLDL na LDL. Kalisiyumu ya Rosuvastatin irashobora guhatanira guhagarika umwijima methylglutaryl coenzyme A reductase. , kandi irongera igira ingaruka nziza mukugabanya ibinure.Ifite ubuzima burebure.Igitsina n'imyaka y'abarwayi nta ngaruka nini bigira kuri metabolism yibiyobyabwenge.