Reductase, glutathione CAS:9001-48-3

Glutathione reductase ni enzyme igira uruhare runini mu kubungabunga uburinganire bwa glutathione yagabanutse kandi ikaranze (GSH / GSSG) mu turemangingo. Glutathione ni tripeptide igizwe na aside amine glycine, cysteine, na glutamate. Ikora nk'ikintu gikomeye kirwanya uturemangingo kandi igira uruhare mu mikorere itandukanye y'uturemangingo, harimo gukurura no gusana ADN, no gukora poroteyine.

Glutathione reductase igabanya glutathione (GSSG) kugeza ku rugero rwayo rugabanutse (GSH) ikoresheje NADPH (nicotinamide adenine dinucleotide phosphate) nk'ikintu gifasha mu gutuma glutathione igabanuka mu turemangingo, kuko GSSG ishobora kwirundanya iyo hari ikibazo cy'imisemburo ya oxidative.

Mu gukomeza igipimo gikwiye cya GSH na GSSG, glutathione reductase ifasha kurinda uturemangingo kwangirika kwa ogisijeni guterwa n’ubwoko bwa ogisijeni (ROS) n’izindi molekile zangiza. Ikora nk'ingenzi mu kurinda uturemangingo twa ogisijeni.

Byongeye kandi, glutathione reductase inagira uruhare mu kongera gukoresha glutathione disulfide (GSSG) ikorwa mu gihe cy'imikorere itandukanye ya metabolic, bigatuma habaho kugabanuka kwa glutathione (GSH) mu mikorere yayo myinshi y'uturemangingo.

Gutumiza cyangwa Gusaba Igiciro

Ibisobanuro birambuye ku gicuruzwa

Ibirango by'ibicuruzwa

Ishyirwa mu bikorwa n'ingaruka

Kugenzura Redox: Glutathione reductase igira uruhare runini mu kubungabunga redox y'uturemangingo. Ifasha mu kubungabunga igipimo gikwiye cya glutathione yagabanutse (GSH) na glutathione ya oxidized (GSSG) binyuze mu guhindura GSSG muri GSH. Iyi redox iringaniza ni ingenzi ku mikorere myinshi y'uturemangingo kandi ni ingenzi cyane ku kubaho no gukora kw'uturemangingo.

Ubwirinzi bwa antioxydants: Glutathione reductase, binyuze mu kubungabunga urugero rwa glutathione rwagabanutse, yongera uburyo bwo kurinda utunyangingo. Glutathione ikora nk'inyangingo ikomeye, ikuraho ubwoko bwa ogisijeni (ROS) n'izindi radicals zangiza zishobora kwangiza utunyangingo no guhangayika.

Gukuraho uburozi: Glutathione reductase igira uruhare mu gukuraho uburozi ku bintu byangiza n'ibiyobyabwenge bya xenobiotics. Yoroshya guhuza ibintu byangiza na glutathione, bigatuma bivanwa mu mubiri.

Imikorere y'ubudahangarwa bw'umubiri: Glutathione reductase igira uruhare runini mu mikorere y'ubudahangarwa bw'umubiri. Ifasha mu kubungabunga imiterere ya redox y'uturemangingo tw'umubiri, ikangura neza uburyo ubudahangarwa bw'umubiri bwitwara, kandi igashyigikira ikwirakwira n'itandukaniro ry'uturemangingo tw'umubiri.

Ikimenyetso cyo gusuzuma no guhanura: Igikorwa cya Glutathione reductase gishobora gupimwa kugira ngo hamenyekane uko redox ihagaze n'urugero rw'umuvuduko wa oxidative mu ndwara zitandukanye. Impinduka mu gikorwa cya glutathione reductase zishobora gukoreshwa nk'ikimenyetso cyo gusuzuma no guhanura indwara zitandukanye, harimo kanseri, indwara z'umutima n'imitsi, indwara z'umwijima, n'indwara zo mu bwonko zitera kwangirika.

Uburyo bwo kuvura: Guhindura imikorere cyangwa imikorere ya Glutathione bishobora gusuzumwa nk'ingamba zo kuvura indwara ziterwa n'imihangayiko ya oxidative, nk'indwara zo mu bwonko, indwara z'umutima n'imitsi, na kanseri zimwe na zimwe.

Gupakira ibicuruzwa:

Amakuru y'inyongera:

Imiterere	NA
Isuzuma	99%
Isura	Amazi y'umuhondo
Nimero ya CAS	9001-48-3
Gupakira	Bito kandi byinshi
Igihe cyo Kubika	Imyaka 2
Ububiko	Bika ahantu hakonje kandi humutse
Icyemezo	ISO.