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N-Acetyl-D-Glucosamine CAS: 7512-17-6 Umukozi Ukora
N-Acetyl-D-Glucosamine ni ubwoko bwa N-acetyl bukomoka kuri glucosamine. Mu buryo bwa shimi, ni amide iri hagati ya glucosamine na aside asetiki. Igice kimwe cya N-acetylglucosamine gifitanye isano na serine cyangwa threonine bisigara kuri poroteyine za kirimbuzi na cytoplasmic -O-GlcNAc, ni ihinduka rya poroteyine rikunze kugaragara nyuma yo guhinduka. Poroteyine zahinduwe na O-GlcNAc zigira uruhare mu kumenya imiterere y'intungamubiri mu bidukikije no guhindura imikorere ya poroteyine z'ingirabuzima fatizo hakurikijwe uko bikwiye. O-GlcNAc igenzura uko ingirabuzima fatizo zisubiza imisemburo nka insuline, itangiza uburyo bwo kurinda stress, ihindura ubushobozi bw'ingirabuzima fatizo bwo gukura no kwigabanyamo ibice, kandi igenzura uburyo ingirabuzima fatizo zikora. Mu bantu, iba mu ruhu, mu gituza no mu mitsi y'amaraso nk'igice cya aside hyaluronic, naho mu magufwa, mu mboni na aorta nk'igice cya keratan sulfate.
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Creatine Pyruvate CAS: 55965-97-4 Umukozi Ukora
Creatine Pyruvate ni ikinyabutabire kirimo Creatine na aside pyruvic kandi gikoreshwa n'abubatsi b'umubiri nk'inyongera kugira ngo kibone ibisubizo byo kutagira ingaruka mbi ku mubiri kandi gishongesha mu mazi burundu. Mu kinyabutabire cyayo Creatine Pyruvate ishongesha inshuro 10 kurusha uko iri mu kinyabutabire. Ubushakashatsi bwagaragaje ko Pyruvate igabanya ibinure mu mubiri idakoresheje poroteyine y'imitsi, ikintu cy'ingenzi mu kugera ku mitsi yoroheje. Inyongeramusaruro za Creatine Pyruvate ni inkunga nziza ku bakinnyi bashaka kongera imikorere y'imitsi no kwihangana muri gahunda z'imyitozo ngororamubiri ikomeye.
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Vitamine A Palmitat CAS: 79-81-2 Umukozi Ukora
Retinyl palmitate iri mu bwoko bw'ibinyabutabire byitwa retinoids, bisa na vitamine A mu buryo bwa shimi. Igira akamaro ku kureba, uruhu n'imikorere y'ubudahangarwa bw'umubiri, ikabuza ikwirakwira ry'uturemangingo no gukumira kanseri. Ni indyo y'ingenzi ndetse n'ikinyabutabire cyo kuvura. All-trans-retinyl palmitate ni ester ya trans-retinyl iboneka mu guhumeka kw'itsinda rya karubokisi rya palmitic (aside hexadecanoic) hamwe na hydroxy group ya all-trans-retinol. Ikoreshwa mu bikoresho byo kwisiga mu kuvura indwara zitandukanye z'uruhu nko kurwara ibiheri, gusaza k'uruhu, iminkanyari, ibizinga byijimye, ndetse no kurinda psoriasis. Ifite uruhare nk'itsinda rya Escherichia coli, itsinda rya xenobiotic mu bantu na antioxydant. Ni retinyl palmitate na all-trans-retinyl ester. Ifitanye isano n'imikorere ya all-trans-retinol.
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Benfotiamine CAS: 22457-89-2 Umukozi Ukora
S-Benzoylthiamine O-monophosphate (Benfotiamine) ni ubwoko bwa S-acyl thiamine bukomoka kuri amphiphilic. Ni vitamine ishonga mu maraso. Benfotiamine irimo impeta ya thiazole. Benfotiamine ifite ubushobozi bwo kuboneka kurusha thiamine.
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Kolajeni Hydrolyzed CAS: 92113-31-0 Umukozi Utanga
Kolajeni ya hydrolyzed yitwa kandi kolajeni ya hydrolyzed. Kolajeni ya hydrolyzed ni ubwoko bushya bw'ibikomoka kuri kolajeni, bikorwa bivuye kuri kolajeni cyangwa umutungo ukura kuri kolajeni. Uretse imiterere ya aside amine ya kolajeni (hafi 30% by'ibisigazwa bya aside amine yose ni glycine), inafite 15-30% bya aside amine ebyiri zidakunze kuboneka mu zindi poroteyine, proline na 4-hydroxyproline Uretse aside), inafite imiterere y'uburemere buto bwa molekile, kandi imiterere yayo igizwe ahanini na peptide nto zifite uburemere bwa molekile buri munsi ya 3000.
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Vitamine E karemano CAS: 59-02-9 Umukozi Ukora
Amavuta ya Vitamine E ni vitamine ishonga mu mavuta, izwi kandi nka tocopherol. Ni imwe mu mavuta y’ingenzi arwanya indwara. Ni ibinyabutabire bishonga mu mavuta nka ethanol, kandi ntibishonga mu mazi, ubushyuhe, ntibihinduka aside, kandi ntibishobora gushonga. Bishobora kwitabwaho na ogisijeni ariko ntibishobora kwitabwaho n’ubushyuhe. Kandi imikorere ya vitamine E yari iciriritse cyane mu gukaranga. α-Tocopherol ikorwa muri γ-tocopherol binyuze mu bikorwa bya enzyme γ-tocopherol methyltransferase. Ni yo bwoko bwa Vitamine E mu maraso y’umuntu. Iboneka mu mavuta y’imbuto z’ibihwagari.
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Curcumin (turmeric) 95% CAS: 458-37-7 Umukozi Utanga
Curcumin ni yo ibara ry'umuhondo rikomeye muri turmeric na curry kandi ifite ibikorwa byo kurwanya antioxidant, kurwanya ububyimbirwe, no kurwanya kanseri. Ibuza gukora nitric oxide (NO) (IC50 = 6 μM) kandi ikagabanya imikorere ya nitric oxide synthase (iNOS) mu turemangingo twa RAW 264.7 twa LPS. Curcumin ibuza irekurwa rya histamine na cytokines zitera ububyimbirwe TNF-α, IL-1β, IL-6, na IL-8 biva mu turemangingo twa HMC-1 mast. Mu mubiri, curcumin igabanya urugero rwa histamine na TNF-α mu maraso, ikabuza impinduka mu mazuru, kandi ikagabanya umubare w'imisatsi no gukaraba izuru mu imbeba ya rhinitis iterwa na ovalbumin.
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Vitamine B1 (Thiamine Hydrochloride) CAS: 67-03-8 Umukozi Ukora
Thiamine Hydrochloride ni umunyu wa hydrochloride wa thiamine (vitamine B1), vitamine y'ingenzi mu mikorere y'umubiri, gukura kw'uturemangingo, kohereza imyumvire y'imitsi no gukora acetylcholine. Vitamine B1 ifasha mu gukumira ibibazo bitandukanye by'ubuzima birimo no kwangirika k'umutima.
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Umukozi ushinzwe gukora Hydroxycobalamin HCL CAS: 78091-12-0
Hydroxycobalamin (ohcbl, cyangwa B12a) ni ubwoko karemano bwa vitamine B12, cyangwa imwe mu matsinda ya vitamine B12. Ni kimwe mu bigize itsinda rya cobalamine. Bagiteri nyinshi zikora vitamine zikora vitamine B12 mu bucuruzi mu buryo bwa hydroxycobalamin. Hydroxycobalamin ni umutuku wijimye. Vitamine B12 mu mubiri w'umuntu ubusanzwe ntabwo iba mu buryo bwa hydroxycobalamin. Ariko, ku bantu, hydroxycobalamin ihinduka byoroshye mu buryo bwa coenzyme ya vitamine B12. Umuti wa hydroxycobalamin ni inshinge yayo idapfa gukoreshwa, ikoreshwa mu kuvura ibura rya vitamine no kuvura uburozi bwa cyanide (kuko ihuye na iyoni za cyanide).
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Kolajeni II CAS: 9064-67-9 Umukozi Ukora
Collagen ni yo igize igice cy’ingenzi cya matrix yo hanze y’umubiri, ikaba ari poroteyine nyinshi z’imiterere y’umubiri mu bice byose byo hejuru. Iboneka cyane cyane mu ngingo z’umubiri nk’uruhu, imitsi n’imitsi mu buryo bwa fibrils ndende, kandi ikaba iboneka no mu mitsi ya cornea, imitsi y’amaraso, amagufwa, cartilage, intervertebral discs no mu mara. Izi ni zo poroteyine nyinshi mu nyamaswa zigize 30% bya poroteyine zose mu mubiri w’inyamaswa.
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Nicotinamide Riboside (Chloride) CAS: 23111-00-4 Umukozi Ukora
Nicotinamide Riboside Chloride ni umunyu wa chloride ukomoka kuri nicotinamide riboside (NR).NR ni ubwoko bushya bwa pyridine-nucleoside ya vitamine B3 ikora nk'intangiriro ya nicotinamide adenine dinucleotide (NAD) cyangwa NAD+. Nicotinamide riboside chloride ni ubwoko bwa kristu bwa Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride yongera urugero rwa NAD[+] kandi igatuma SIRT1 na SIRT3 birushaho gukora, bikagera ku rwego rwo kongera imikorere ya oxidative no kurinda indwara ziterwa n'ibinure byinshi mu mirire. Nicotinamide riboside chloride ikoreshwa mu nyongeramusaruro mu mirire.
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D-Fructose 1,6-Disphosphate Trisodium Umunyu CAS: 38099-82-0
Fructose-1,6-biphosphate (F1,6P) ni glycolytic intermediate ikorwa no kwimura fosfeti kuva kuri ATP ijya kuri fructose-6-phosphate hakoreshejwe enzyme phosphofructokinase. Fructose-1,6-biphosphate, hamwe na fructose-2,6-biphosphate, ihindura imikorere ya phosphofructokinase-1 (PFK-1), intambwe igabanya igipimo muri glycolysis. Mu gihe cya glycolysis, aldolase igabanya Fructose-1,6-biphosphate muri dihydroxacetone phosphate (DHAP) na glyceraldehyde phosphate. Fructose-1,6-biphosphate nayo ni allosteric activator ya M2 isoform ya Pyruvate Kinase (PK-M2), ubwoko bwiganje bwa pyruvate kinase mu turemangingo twa kanseri.
