N-Acetyl-D-Glucosamine CAS: 7512-17-6 Umukozi Ukora

N-Acetyl-D-Glucosamine ni ubwoko bwa N-acetyl bukomoka kuri glucosamine. Mu buryo bwa shimi, ni amide iri hagati ya glucosamine na aside asetiki. Igice kimwe cya N-acetylglucosamine gifitanye isano na serine cyangwa threonine bisigara kuri poroteyine za kirimbuzi na cytoplasmic -O-GlcNAc, ni ihinduka rya poroteyine rikunze kugaragara nyuma yo guhinduka. Poroteyine zahinduwe na O-GlcNAc zigira uruhare mu kumenya imiterere y'intungamubiri mu bidukikije no guhindura imikorere ya poroteyine z'ingirabuzima fatizo hakurikijwe uko bikwiye. O-GlcNAc igenzura uko ingirabuzima fatizo zisubiza imisemburo nka insuline, itangiza uburyo bwo kurinda stress, ihindura ubushobozi bw'ingirabuzima fatizo bwo gukura no kwigabanyamo ibice, kandi igenzura uburyo ingirabuzima fatizo zikora. Mu bantu, iba mu ruhu, mu gituza no mu mitsi y'amaraso nk'igice cya aside hyaluronic, naho mu magufwa, mu mboni na aorta nk'igice cya keratan sulfate.