Mirabegron CAS: 223673-61-8 Utanga ibicuruzwa

Mirabegron ni iyo kuvura byihutirwa, inshuro nyinshi zinkari, hamwe ninkari zinkari zinkari zifitanye isano nuruhago rukabije (OAB).Mirabegron ikomatanyirizwa hamwe no guhuza 4-nitropenethyl amine na (R) -2-hydroxy-2-acide fenylacetic.Amide yavuyemo yagabanutse kuri amine.Itsinda rya nitro noneho rigabanuka hanyuma ibivuyemo bigahuzwa na 2- (2-aminothiazol-4-yl) acide acike kugirango itange mirabegron.

Tegeka cyangwa usabe amagambo

Ibicuruzwa birambuye

Ibicuruzwa

Gushyira mu bikorwa n'ingaruka

Mirabegron ni umunwa ukora β3-adrenoeptor agonist kuri ubu uri gutezwa imbere na Astellas Pharma yo kuvura uruhago rukabije (OAB).Ibiyobyabwenge ni nanomolar EC50 irwanya abantu β3-AR ibinyabuzima byangiza imiti hamwe no guhitamo neza kuri b1- na β2-ARs.Mirabegron yerekana uburyo bushya yibanda kuri β3-AR yo kuruhuka uruhago kugirango ifashe gucunga ibimenyetso bya OAB nko kongera inkari byihutirwa hamwe ninshuro no kutihutirwa.Nyamara, mirabegron ni cytochrome P450 2D6 inhibitor, kandi itera impungenge zo guhuza ibiyobyabwenge-ibiyobyabwenge nubuyobozi bufatanije nubundi buryo bwa cytochrome P450 2D6.

Icyitegererezo cyibicuruzwa

Gupakira ibicuruzwa:

Amakuru yinyongera:

Ibigize	C21H24N4O2S
Suzuma	99%
Kugaragara	Ifu yera yijimye
URUBANZA No.	223673-61-8
Gupakira	25KG
Ubuzima bwa Shelf	Imyaka 2
Ububiko	Ubike ahantu hakonje kandi humye
Icyemezo	ISO.