Leflunomide CAS: 75706-12-6 Umutanga serivisi w'umukozi Ishusho y'umwihariko

Leflunomide CAS: 75706-12-6 Umukozi Ukora

Leflunomide ni umuti uvura indwara ziterwa n’imiti ya rubagimpande uboneka mu kanwa, ukaba warashyizwe ahagaragara muri Amerika witwa Arava mu kuvura indwara ya rubagimpande (RA); ni wo muti wa mbere kandi wonyine wagaragajwe ko ugabanya kwangirika kw’ingingo za RA, bityo ugakemura ikibazo cy’ubuvuzi kidakemutse. Leflunomide ni umuti ufasha mu guhindura imikorere y’umubiri vuba kandi hafi ya bwose (igice cy’ubuzima,

Gutumiza cyangwa Gusaba Igiciro

Ibisobanuro birambuye ku gicuruzwa

Ibirango by'ibicuruzwa

Ishyirwa mu bikorwa n'ingaruka

Leflunomide ntabwo ikora, ariko teriflunomide ibuza pyrimidine de novo synthesis ku gipimo gito cyo kuvura binyuze mu kubuza dihydroorotate dehydrogenase (enzyme igena igipimo cyo gukora UMP), kugabanya imikorere ya ADN na RNA, no guhagarika ubwiyongere bw'uturemangingo no gukora antibody. Kugabanuka kwa dihydroorotate kuri orotate bibaho rimwe na kugabanuka kwa cofactor yayo, ubiquinone (coenzyme Q). Kubuza dihydroorotate dehydrogenase na teriflunomide bigaragaza kinetics idahiganwa kandi idahiganwa. Gutanga leflunomide ku barwayi ba rubagimpande bituma uturemangingo twa B dukurwaho buhoro buhoro kandi bigatuma ubudahangarwa bw'umubiri bugabanuka.

Urugero rw'ibicuruzwa

Gupakira ibicuruzwa:

Amakuru y'inyongera:

Imiterere	C12H9F3N2O2
Isuzuma	99%
Isura	Ifu y'umweru
Nimero ya CAS	75706-12-6
Gupakira	25KG
Igihe cyo kuruhuka	Imyaka 2
Ububiko	Bika ahantu hakonje kandi humutse
Icyemezo	ISO.