Hygromycin B CAS:31282-04-9 Igiciro cy'umukozi

Hygromycin B ni umuti urwanya udukoko ukomoka kuri bagiteri ya Streptomyces hygroscopicus. Igira ingaruka nziza mu kubuza poroteyine mu turemangingo mu kubangamira imikorere ya peptidyl transferase ya ribosomu. Hygromycin B igira ingaruka nziza ku bwoko bwinshi bwa bagiteri, ibihumyo, n'uturemangingo twinshi twa eukaryotic.

Imwe mu mikoreshereze ikomeye ya Hygromycin B ni nk'ikintu gitoranya mu bushakashatsi bwa molekile no mu bushakashatsi bw'ubuhanga mu by'uturemangingo. Ikunze gukoreshwa nk'ikimenyetso gitoranya mu gukora ibinyabuzima byahinduwe mu ngirabuzimafatizo, nk'ibimera, inyamaswa, na bagiteri. Mu gushyiramo uburyo bwo kurwanya Hygromycin B mu ngirabuzimafatizo, abashakashatsi bashobora kumenya no guhitamo uturemangingo cyangwa ibinyabuzima byashyize mu bikorwa impinduka zifuzwa mu ngirabuzimafatizo.

Kugira ngo uturemangingo cyangwa ibinyabuzima bikoreshwe Hygromycin B mu gutoranya, ubusanzwe uturemangingo cyangwa ibinyabuzima bivurwa na antibiyotike. Uturemangingo twashoboye guhuza neza gene yo kurwanya indwara ni two twonyine dushobora kubaho no gukomeza gukura, mu gihe uturemangingo tutarahinduka dupfa. Ibi bituma abashakashatsi bashobora gutandukanya no gukwirakwiza uturemangingo twahinduwe gene twifuza kugira ngo dukoreshwe mu bushakashatsi cyangwa mu buryo burambuye.

Uretse gukoreshwa kwayo mu buhanga mu by’uturemangingo, Hygromycin B ikoreshwa kandi nk'umuti urwanya udukoko no kurwanya udukoko mu buryo butandukanye bw’ubushakashatsi. Ikoreshwa mu buryo bwo guteza imbere uturemangingo kugira ngo hirindwe kwanduzwa na bagiteri, ibihumyo, n’utundi dukoko dushobora kubangamira iterambere n’inyigo y’uturemangingo.