Fmoc-Asp(OBut)-OSu CAS:78553-23-8

Fmoc-Asp (OBut)-OSu ikora nk'igikoresho gifite imikorere myinshi mu gukora peptide, cyane cyane mu gukora peptide zirimo aside aspartike neza. Itsinda ririnda Fmoc rikingira itsinda rya amino, rigatanga ibisubizo byihariye mu gihe cyo guhuza peptide, mu gihe itsinda rya O-butyl ryongeraho urwego rw'inyongera rw'uburinzi ku itsinda rya carboxyl. Imikorere ya OSu ester yorohereza ikorwa ry'imigozi ya amide neza kandi itoranya mu gihe cyo guhuza peptide. Abashakashatsi bakoresha cyane Fmoc-Asp (OBut)-OSu mu gukora peptide mu bikorwa bitandukanye, harimo guteza imbere imiti, ibikoresho bya biomaterial, no gushushanya peptide zikora neza zifite imiterere yihariye. Ihuye n'uburyo busanzwe bwo gukora peptide, haba mu ngamba zikomeye no mu cyiciro cy'ibisubizo, yongera imikorere yayo mu bushakashatsi butandukanye. Gukuraho amatsinda arinda bigenzurwa bituma aside aspartike ishyirwa mu buryo bw'ingamba, bikongera urwego rwa peptide zishobora gukorwa. Byongeye kandi, Fmoc-Asp (OBut)-OSu ibona akamaro mu gukora peptide mu bushakashatsi bwa proteomics no kwiga imikorere y'uturemangingo. Ikoreshwa ry’itsinda rishinzwe kurinda O-butyl rituma habaho uburyo bwo gukora neza aside aspartic reactivity, naho itsinda rya ester rya OSu rifasha guhuza no gushyira ibirango bya peptides. Muri make, Fmoc-Asp (OBut)-OSu ni igikoresho cy’ibanze kandi cy’ingenzi mu buhanga bwa peptide, giha abashakashatsi ububasha bwo gushakisha no guhindura reactivity ya aside aspartic ku buryo butandukanye bwo gukoresha mu bushakashatsi, cyane cyane bakibanda kuri peptides zifite imikorere myiza binyuze mu itsinda rya ester rya OSu.