Fmoc-Asn(Trt)-OH CAS:132388-59-1

Fmoc-Asn (Trt)-OH ifite umwanya w'ingenzi mu gukora peptide, cyane cyane mu guteranya peptide zirimo asparagine. Itsinda ririnda Fmoc rikingira itsinda rya amino, rigatanga ibisubizo byihariye mu gihe cyo guhuza peptide, mu gihe itsinda rya trityl ritanga ubundi buryo bwo kurinda. Abashakashatsi bakoresha cyane Fmoc-Asn (Trt)-OH mu gukora peptide mu bikorwa bitandukanye, harimo guteza imbere imiti, ibikoresho by'ibinyabuzima, no gushushanya peptide zikora. Ihuye n'uburyo busanzwe bwo gukora peptide, haba mu ngamba zikomeye no mu cyiciro cy'ibisubizo, byongera akamaro kayo mu bushakashatsi butandukanye. Gukuraho amatsinda arinda bigenzurwa bituma asparagine ishyirwa mu buryo bwa peptide, bigatera imbere ku budasa bwa peptide zishobora gukorwa. Byongeye kandi, Fmoc-Asn (Trt)-OH ibona akamaro mu gukora peptide mu bushakashatsi bwa proteomics no mu kwiga imikorere y'uturemangingo. Imikoreshereze y’itsinda rishinzwe kurinda trityl ituma habaho gukoresha neza uburyo asparagine ikorwa, biha abashakashatsi igikoresho cy’agaciro cyo gushushanya peptides zifite impinduka zihariye. Muri make, Fmoc-Asn (Trt)-OH ni igikoresho cy’ingenzi kandi gifite akamaro kanini mu bijyanye na peptides, giha abashakashatsi ubushobozi bwo gusesengura no guhindura uburyo asparagine ikorwamo mu buryo butandukanye bwa siyansi.