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Ethyl oxalyl monochloride CAS: 4755-77-5
Ethyl oxalyl monochloride ni ikintu cy’ingenzi kigizwe n’itsinda rya ethyl rifatanye n’igice cya oxalyl, gifite amatsinda abiri ya karuboni na atome imwe ya chlorine. Hamwe na formula ya molekile C5H7ClO3, iki kintu kizwi cyane nk'ikintu cy’ingenzi mu guhuza imiterere y’ibinyabuzima, cyane cyane mu nganda zikora imiti n’ibikomoka ku buhinzi. Uburyo kidasanzwe cyacyo gikomoka ku mikorere ya oxalyl na chlorine, bigatuma kigira uruhare mu mpinduka zitandukanye z’ibinyabutabire. Abashakashatsi basuzumye ethyl oxalyl monochloride kugira ngo barebe akamaro kayo mu gukora molekile zikomeye zifite ibikorwa bitandukanye by’ibinyabuzima.
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DL-4-Chlorophenylglycine CAS: 6212-33-5
DL-4-Chlorophenylglycine ni ikinyabutabire cyakunzwe cyane mu bijyanye n'ubutabire bw'imiti n'imiti. Nk'ikinyabutabire cya glycine, gifite itsinda rya chlorophenyl, rikongera imiterere yacyo yo gufatanya n'imikorere ya biyoloji. Iki kinyabutabire cyakoreweho ubushakashatsi ku mikoreshereze yacyo mu kuvura indwara zitandukanye z'imitsi, cyane cyane binyuze mu guhindura uburyo bwa glutamate receptors. Imiterere yihariye ya DL-4-Chlorophenylglycine inayifasha gukora nk'umurwanyi cyangwa agonist bitewe n'ibidukikije, bigatuma iba umukandida ukoreshwa mu bushakashatsi ku buvuzi bw'imitsi. Ikorwa ryayo n'imiterere yayo bikomeje kuba ahantu hakorerwa ubushakashatsi bukomeye.
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URUBANZA RWA DRONEDARONE HYDROCHLORIDE: 141625-93-6
Dronedarone hydrochloride ni umuti urwanya arrhythmia ukoreshwa cyane cyane mu kuvura atrial fibrillation na atrial flutter. Iyi dronedarone ikomoka kuri amiodarone, yakozwe kugira ngo itange inyungu nk'izo mu kuvura ariko igagabanya zimwe mu ngaruka mbi ziterwa na amiodarone, cyane cyane uburozi bwayo bwa tiroyide n'ubuhumekero. Dronedarone ikora mu kongera imbaraga zo gukora no kumara igihe kinini mu ngingo z'umutima, igatuza umutima, kandi ikagabanya ibyago byo kujya mu bitaro bitewe n'indwara z'umutima n'imitsi. Yemejwe gukoreshwa mu buvuzi mu bihugu bitandukanye, dronedarone ni intambwe ikomeye mu micungire y'imiti ya atrial arrhythmias.
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aside valproic CAS:99-66-1
Aside Valproic, izwi kandi nka aside 2-propylpentanoic, ni umuti ukoreshwa cyane mu kuvura indwara zo mu mutwe no mu gutuma umuntu ahora yumva ameze neza, cyane cyane ukoreshwa mu kuvura igicuri n'indwara yo mu mutwe. Yavumbuwe mu myaka ya 1960, ikora mu kongera urugero rwa aside gamma-aminobutyric (GABA) mu bwonko, ikaba ari yo ngirabuzimafatizo y'ingenzi ifasha mu kugabanya ubushyuhe bw'imitsi. Aside Valproic yamenyekanye cyane kubera ubushobozi bwayo mu kuvura indwara zo mu mutwe, ndetse no mu gukumira indwara zo mu mutwe no kuvura indwara zimwe na zimwe zo mu mutwe. Imiterere yayo myiza mu buvuzi ituma iba umuti w'ingenzi mu buvuzi bw'imitsi no mu buvuzi bw'indwara zo mu mutwe.
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Sodium Valproate CAS: 1069-66-5
Sodium valproate, umunyu wa sodium ukomoka kuri aside valproic, ni umuti ugabanya ububabare bw'umutima kandi ugatuma umuntu agira ibyiyumvo bihamye ukoreshwa cyane cyane mu kuvura igicuri n'indwara ya bipolar. Ukora mu kongera urugero rwa aside gamma-aminobutyric (GABA) mu bwonko, umusemburo w'ubwonko ugira uruhare runini mu kugabanya gushyuha kw'imitsi. Yemejwe mu mpera z'ikinyejana cya 20, sodium valproate izwiho kugira akamaro mu bwoko butandukanye bw'igicuri kandi ikoreshwa mu gukumira migraine. Imiterere yayo myiza mu buvuzi yatumye iba uburyo bw'ingenzi mu buvuzi bw'imitsi n'indwara zo mu mutwe.
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ETHYL 5-AMINOBENZOFURAN-2-CARBOXYLATE CAS:174775-48-5
Ethyl 5-aminobenzofuran-2-carboxylate ni ikinyabutabire kiri mu bwoko bw'ibikomoka kuri benzofuran, bifite akamaro mu buvuzi bitewe n'ibikorwa byabyo bitandukanye bya biyoloji. Iki kinyabutabire gifite itsinda ry'imikorere ya ethyl ester hamwe n'impinduka za amino ku mpeta ya benzofuran, bigatuma kiba inkingi ikomeye yo gukora molekile zikora neza. Ethyl 5-aminobenzofuran-2-carboxylate yakuruye ibitekerezo mu bushakashatsi bw'imiti kubera uburyo ishobora gukoreshwa mu guteza imbere imiti mishya, cyane cyane mu bice nko kuvura indwara zitera ububyimbirwe, kugabanya ububabare, cyangwa kurwanya mikorobe, bitewe n'imiterere yihariye y'imiterere itangwa n'itsinda rya benzofuran.
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Diethyl benzylmalonate CAS: 607-81-8
Diethyl benzylmalonate ni ikintu cy'ingenzi kigizwe n'ibinyabuzima gikoreshwa cyane mu butabire bw'ubukorano, cyane cyane mu gutegura imiti itandukanye n'ibikomoka ku buhinzi. Iki kintu kigizwe n'ibikomoka kuri aside malonic gifite amatsinda abiri ya ethyl ester n'ikindi kigizwe n'ibikomoka kuri benzyl, ibyo bikaba byongera ubushobozi bwayo mu gukora ibikorwa byo gusimbuza ibinyabuzima. Diethyl benzylmalonate ikora nk'inkingi ikomeye mu gukora molekile zikora neza, harimo n'ibintu by'ingenzi mu iterambere ry'imiti. Imiterere yayo yihariye n'imikorere yayo bituma iba ikintu cy'ingenzi mu butabire bw'imiti, bigatuma abahanga mu butabire bashakisha inzira zitandukanye zo gukoramo imiti kugira ngo bateze imbere uburyo bushya bwo kuvura.
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Indazole CAS: 271-44-3
Indazole ni ikintu gihumeka gikozwe mu buryo bwa bicyclic kigizwe n'impeta ya pyrazole ifite ibice bitanu ivanze n'impeta ya benzene ifite ibice bitandatu. Iyi miterere ya heterocyclic izwiho ibikorwa bitandukanye bya biyolojiya n'ikoreshwa ryayo mu buvuzi. Indazole n'ibiyikomokaho byakunzwe cyane kubera uruhare rwayo mu miterere itandukanye ya farumasi, nko kurwanya ububyimbirwe, kurwanya kanseri, no kurwanya mikorobe. Iki kintu gikora nk'inkingi y'ingenzi mu iterambere ry'imiti, cyane cyane mu gushushanya imiti mishya yibasira indwara nyinshi. Ubushakashatsi bukomeje gukorwa ku buryo bwo gukorana n'imiti n'ingaruka za biyolojiya zijyanye na indazole.
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ETHYL 5-NITROBENZOURAN-2-CARBOXYLATE CAS:69604-00-8
Ethyl 5-nitrobenzofuran-2-carboxylate ni ikintu gikomeye mu rwego rwa chimie organic, cyane cyane mu rwego rwa heterocyclic compounds. Nk'ikintu gikomoka kuri benzofuran cyasimbuwe na nitro, kigaragaza imiterere yihariye ya shimi n'ibikorwa bya biyoloji bituma iba intego ikurura ubushakashatsi ku buvuzi. Kuba iri mu itsinda rya nitro byongera uburyo ikora, bigatuma ishobora gukoreshwa mu gukora imiti mishya. Ethyl 5-nitrobenzofuran-2-carboxylate yakuruye abantu benshi kubera uburyo ishobora gukoreshwa mu guteza imbere imiti irwanya ububyimbirwe, irwanya udukoko, na kanseri, bigaragaza akamaro kayo mu guteza imbere chemistry y'ubuvuzi n'ingamba zo kuvumbura imiti.
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4-Bromophenylacetone CAS: 6186-22-7
4-Bromophenylacetone ni ketone ihumura neza irangwa n'ikintu gisimbura bromine ku mpeta ya phenyl, hamwe n'itsinda ry'imikorere ya acetone. Iki kintu cyakuruye ubwitabire mu gukora organic bitewe n'uburyo gikoreshwa mu guteza imbere molekile zigoye cyane, harimo imiti n'ibinyabutabire by'ubuhinzi. Kuba atome ya bromine iriho byongera imiterere yayo ikora neza, bigatuma habaho imikorere itandukanye mu buryo bwo gukora. Byongeye kandi, 4-bromophenylacetone yagaragaje ibikorwa bishobora gukorwa mu binyabuzima, bituma ishishikazwa n'imiti ikoreshwa mu bushakashatsi no mu ikoreshwa mu kuvumbura imiti.
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4-Hydroxyphenylacetone CAS: 770-39-8
4-Hydroxyphenylacetone ni ketone ihumura neza ifite itsinda rya hydroxyl rifatanye n'impeta ya phenyl n'igice cya acetone. Iki kinyabutabire kizwiho ikoreshwa mu buryo butandukanye mu guhuza ibinyabuzima n'imiti. Gikora nk'igice cy'ingenzi mu gutegura imiti itandukanye, imiti ikomoka ku buhinzi, n'imiti myiza. Kuba iri muri iryo tsinda rya hydroxy byongera uburyo rikora kandi rigatuma habaho izindi mpinduka, bigatuma riba urwego rw'agaciro mu guteza imbere imiti. Ubushakashatsi kuri 4-hydroxyphenylacetone bwagaragaje ibikorwa byayo bya biyoloji, birimo imiterere ya antioxidant n'irwanya ububyimbirwe, bigira uruhare mu bumenyi bw'imiti.
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3-(4-Chlorbutyl)-1H-indol-5-carbonitril CAS:143612-79-7
3-(4-Chlorobutyl)-1H-indol-5-carbonitrile ni ikomoka kuri indole irangwa n'uruvange rwihariye rw'amatsinda y'imikorere ya indole na nitrile, hamwe n'uruhererekane rw'inyuma rwa chlorobutyl. Iki kinyabutabire cyakunzwe cyane mu bijyanye n'imiti bitewe n'ibikorwa byacyo bya biology, bishobora kuba birimo imiti irwanya udukoko, imiti irwanya ubushyuhe, n'imiti irwanya kanseri. Ingufu za indole zikora nk'umugongo ukoresha imiti myinshi, mu gihe kuba hari itsinda rya chlorobutyl byongera ubushobozi bwayo bwo gukora imiti, bigashobora kunoza uburyo umubiri ubonekamo. Ubushakashatsi buri gukorwa bugamije gusuzuma uburyo bwo kuvura n'uburyo iki kinyabutabire gikoreshwa.
