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![1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one CAS:6969-71-7](https://cdn.globalso.com/xindaobiotech/1K37N24IWHVCSAAU3833116.png)
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one CAS:6969-71-7
1,2,4-Triazolo [4,3-a]pyridin-3 (2H)-one ni ikintu kivamo umwuka uhindagurika gihuza impeta ya triazole n'imiterere ya pyridine. Iyi molekile irimo imiterere ikora irimo azote, ituma igira uruhare mu miterere itandukanye y'ibinyabutabire n'ibikorwa byayo bya biyoloji. Yashishikajwe n'imiti ya chimie bitewe n'uko ishobora gukoreshwa nk'umuti urwanya mikorobe, urwanya ububyimbirwe, cyangwa urwanya kanseri. Kuba hari igice cya triazole byongera imikoranire yacyo n'ibintu bitandukanye bya biyoloji, bigatuma kiba umuti mwiza wo guteza imbere imiti. Ubushakashatsi buri gukorwa bugamije gusobanura imiterere yacyo mu by'imiti no gushakisha ubushobozi bwayo mu kuvura mu nzego zitandukanye z'ubuvuzi.
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2-PIPERIDYLMETHYLAMINE CAS: 22990-77-8
2-Piperidylmethylamine ni ikintu cy’umwimerere gifite impeta ya piperidine ifite itsinda rya methylamine rifatanye n’ahantu habiri. Iyi miterere iha imiterere yihariye ya shimi n’ibikorwa bishobora gukorwa mu buzima. Nk’ikiva muri piperidine, ishobora gukorana n’ibintu bitandukanye byakira imiterere y’umubiri n’imisemburo mu buryo bw’ibinyabuzima, bigaragaza ko ishobora gukoreshwa mu buvuzi. Bitewe n’imikorere yayo ya amine, 2-piperidylmethylamine ishobora kugira uruhare mu guhuza hydrogen, igira ingaruka ku gushonga kwayo no guhuza imiterere y’ibintu biyigize. Ubushakashatsi bwayo bushobora gutuma habaho kuvumbura mu iterambere ry’imiti, cyane cyane mu nzego zijyanye na neuropharmacology no kuvura indwara zo mu mutwe.
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4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene CAS:173336-76-0
4-Bromo-1-methoxy-2- (3-methoxy-propoxy)-benzene ni imvange y’ibinyabuzima izwiho kuba ikoreshwa mu bintu byayo bya bromine na methoxy, bigira uruhare mu miterere yayo yihariye ya shimi. Imiterere yayo ifite impeta ya benzene ifite itsinda rya bromo ku mwanya wa para n’amatsinda abiri ya methoxy, rimwe riri kuri karuboni ya mbere n’irindi riri mu muyoboro wa propoxy ufatanye na karuboni ya kabiri. Iyi mvange ishobora kugaragaza ibikorwa bishimishije bya biyoloji bitewe n’uko ishobora gukorana n’ibintu bitandukanye bya elegitoroniki cyangwa enzymes. Ikorwa ryayo n’ibikomoka kuri yo bishobora gusuzumwa kugira ngo bikoreshwe mu miti, mu buhinzi, no mu bumenyi bw’ibikoresho, bigatanga ubumenyi bw’ingirakamaro ku buryo ikora n’akamaro kayo.
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5-BROMOINDOLINE CAS: 22190-33-6
5-Bromoindoline ni ikintu cy’umwimerere kiri mu muryango wa indoline, kirangwa no kuba hari atome ya bromine ku mwanya wa 5 w’urwego rwa indoline. Uku gusimbuza kudasanzwe byongera uburyo bwo gukora imiti kandi bigatanga imiterere itandukanye ishobora kuba ingirakamaro mu bikorwa bitandukanye, harimo ubutabire bw’imiti n’ubumenyi bw’ibikoresho. Indolines zizwiho ibikorwa byazo bya biyoloji kandi ziboneka mu bicuruzwa byinshi bisanzwe n’ibinyabutabire bifitanye isano n’imiti. Kwinjizwa kwa bromine bishobora guhindura imiterere y’icyo kintu cya elegitoroniki, bishobora kugira ingaruka ku mikoranire yacyo n’ibintu bigamije biyoloji, bigatuma 5-bromoindoline iba ikintu cy’ingenzi mu gushushanya no guteza imbere imiti.
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3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate CAS:179688-53-0
3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate ni ikinyabutabire kiri mu muryango wa quinazoline. Iki kinyabutabire gifite imiterere yihariye irangwa n'ishingiro rya quinazolinone rifite itsinda rya acetate n'ikintu gisimbura methoxy. Ibikorwa byacyo bya biyoloji byakuruye ubwinshi mu buvuzi, cyane cyane kubera ingaruka zacyo mu iterambere ry'imiti. Ubushakashatsi bw'ibanze bwerekana ko iki kinyabutabire gishobora kugaragaza imiterere ya bagiteri, imiti yica udukoko, cyangwa kanseri, nubwo hakenewe ubushakashatsi bwinshi kugira ngo dusobanukirwe neza ingaruka zacyo mu buvuzi n'uburyo kibikora. Muri rusange, 3,4-dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate ni umukandida mwiza wo gukora iperereza ryimbitse mu mikoreshereze y'imiti.
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4-Nitro-2,3-lutidine-N-oxide CAS: 37699-43-7
4-Nitro-2,3-lutidine-N-oxide ni imvange y’umwimerere irimo impeta ya pyridine yasimbuwe n’itsinda rya nitro riri ku mwanya wa 4 n’itsinda ry’imikorere ya N-oxide. Kuba hari imigabane ya nitro na N-oxide bigira ingaruka zikomeye ku mikorere yayo ya shimi n’imiterere yayo, bigatuma igira akamaro mu nzego zitandukanye nko mu buhanga bwa shimi bw’umwimerere n’ubumenyi bw’ibikoresho. Iyi mvange ishobora kuba ingenzi mu guhuza imiti n’ibinyabutabire by’ubuhinzi bitewe n’ubushobozi bwayo bwo gukomeza gukora. Imiterere yayo yihariye ituma irushaho kuba iy’ingenzi mu kwiga ingaruka zo gukuramo electron n’uruhare rwayo mu mikorere yayo.
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5-Methoxytryptamine CAS: 608-07-1
Tryptamine ni imvange ya monoamine ikomoka kuri aside amine tryptophan. Ifite imiterere ya indole ring, iranga ibintu byinshi bikora mu buzima. Tryptamine izwiho uruhare rwayo nk'umusemburo w'ubwonko n'umusemburo w'ubwonko mu bwonko bw'umuntu, igira ingaruka ku mikorere itandukanye y'umubiri nko kugenzura amarangamutima n'uburyo bwo gusinzira. Byongeye kandi, tryptamine ikora nk'intangiriro y'ibintu byinshi by'ingenzi, birimo serotonin na melatonin. Bitewe n'uko imiterere yayo isa n'indi miti ikora ku mitekerereze, yanakoreweho ubushakashatsi ku ngaruka ishobora kugira ku bwenge no ku myumvire, bituma ishishikazwa n'ubushakashatsi mu by'imitsi n'ubuvuzi bw'imitekerereze.
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1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride CAS:52605-52-4
1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride ni ikintu cy’ubukorano gikomoka mu muryango wa piperazine, kizwiho imiterere itandukanye y’imiti. Iyi molekile ifite impeta ya piperazine yasimbuwe n’itsinda rya 3-chlorophenyl n’uruhererekane rwa 3-chloropropyl, bigira uruhare mu mikorere yayo ya biyoloji. Iyi molekile ishobora kugira ingaruka zitandukanye ku mikorere y’imitsi yo hagati, bigatuma ishishikazwa n’imiti n’imiti. Imiterere yayo yihariye igaragaza ko ishobora gukoreshwa mu guteza imbere imiti ivura, cyane cyane mu kuvura indwara zo mu mutwe cyangwa izindi ndwara ziterwa no guhindura uburyo bwo gutuma imitsi ikora. Ariko, ubushakashatsi bwiyongereyeho burakenewe kugira ngo hamenyekane uburyo bwihariye n’ubushobozi bwayo.
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6-Ethyl-3-oxa-6-azaoctanol CAS:140-82-9
6-Ethyl-3-oxa-6-azaoctanol ni ikintu gikozwe mu buryo bwa sintetike kirangwa n'imiterere yacyo yihariye, irimo imikorere ya ether na amine. Iyi molekile ifite urunigi rwa karuboni umunani hamwe n'itsinda rya ethyl kuri karuboni ya gatandatu na heteroatom mu mugongo wayo, bigira uruhare mu bikorwa byayo bya biyoloji. Kuba hariho atome ya ogisijeni mu runigi bigaragaza ko ishobora gukoreshwa mu buhanga mu buvuzi no mu bumenyi bw'ibikoresho. Ubushakashatsi bw'ibanze bushobora kwerekana akamaro kayo mu iterambere ry'imiti cyangwa nk'intangiriro y'impinduka mu bindi binyabutabire. Ariko, ubushakashatsi bwuzuye burakenewe kugira ngo harebwe imiterere yayo yihariye, imikorere yayo, n'ikoreshwa ryayo mu nzego zitandukanye.
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2,5-Bis(2,2,2-trifluoroethoxy) aside benzoic CAS:35480-52-5
Aside benzoic ya 2,5-Bis (2,2,2-trifluoroethoxy) ni imvange y’ibinyabuzima irangwa n’ishingiro rya aside benzoic riri ku ruhande rw’amatsinda abiri ya 2,2,2-trifluoroethoxy ku myanya ya 2 na 5. Imvange ya trifluoroethoxy itanga imiterere yihariye ya shimi kuri molekile, harimo kwiyongera kwa lipophilicity no guhagarara neza mu bihe bitandukanye. Iyi mvange ishishikajwe n’ubumenyi bw’imiti n’ibikoresho bitewe n’uko ishobora gukoreshwa mu gukora imiti no nk'inkingi y’inyubako y’ibikoresho bigezweho. Ubushakashatsi buri gukorwa bugamije gusuzuma uburyo ikora n’imikoranire yayo, ndetse n’ingaruka zishobora guterwa n’ibinyabutabire bya fluorine.
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5-METHOXY-PYRIDINE-3-CARBALDEHYDE CAS:113118-83-5
5-Methoxy-Pyridine-3-Carbaldehyde ni imvange y’ibinyabuzima irangwa no kuba hari itsinda rya methoxy n’itsinda rikora aldehyde rifatanye n’impeta ya pyridine. Iyi mvange ifite umugongo wa pyridine hamwe n’itsinda rya methoxy ku mwanya wa 5 na aldehyde ku mwanya wa 3. Izwiho ubwiza bwayo bw’impumuro nziza kandi ikoreshwa mu gukora imiti itandukanye. Kuba iri itsinda rya methoxy byongera ubushobozi bwayo bwo gukora no gushonga, bigatuma iba ingenzi mu iterambere ry’imiti n’ibinyabutabire by’ubuhinzi.
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5-AMINO-2-METHOXY-3-METHYLPYRIDINEHCL CAS:867012-70-2
5-Amino-2-methoxy-3-methylpyridine hydrochloride (C8H10N2O) ni imvange y’ibinyabuzima irangwa n’impeta ya pyridine ifite amino na methoxy substituents. Kuba hari itsinda rya amino (-NH2) ku mwanya wa 5, itsinda rya methoxy (-OCH3) ku mwanya wa 2, n’itsinda rya methyl ku mwanya wa 3 byongera uburyo bwo gukora ibinyabutabire n’imikorere yabyo. Iki mvange gishishikajwe n’iterambere rya chimie mu buvuzi n’imiti bitewe n’uburyo gishobora gukoreshwa mu kuvura.
