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3,3-Dimethyl-1-Butyne CAS:917-92-0
3,3-Dimethyl-1-butyne ni imvange y’ibinyabutabire izwiho imiterere yayo ya triple bond hamwe n’amatsinda abiri ya methyl afatanye na atome za karuboni zo muri triple bond. Ikunze kwitwa tetramethylethyne kandi ikoreshwa mu buryo butandukanye bwo gukora chemical synthesis.
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6-Chloro-3-methyluracil CAS: 4318-56-3
6-Chloro-3-methyluracil ni ikintu kiva muri uracil, ishingiro rya pyrimidine, hamwe n'amatsinda ya chlorine na methyl afatanye n'ahantu runaka ku ruziga rwa uracil. Uku guhinduka gutanga imiterere yihariye ya shimi na biyoloji muri icyo kintu, bigatuma kiba ingenzi mu bushakashatsi ku buhanga mu by'imiti no mu buvuzi bwa biochemical. Imiterere ya 6-Chloro-3-methyluracil igira ingaruka ku mikoranire yayo mu buryo bw'ibinyabuzima, cyane cyane mu gukora aside nucleic no gukumira enzymes, ari byo bintu by'ingenzi mu gushushanya imiti no guteza imbere uburyo bwo kuvura.
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4-Isothiocyanato-2-(trifluoromethyl)benzonitrile CAS:143782-23-4
4-Isothiocyanato-2- (trifluoromethyl)benzonitrile ni ikinyabutabire kirangwa n'itsinda ry'imikorere ya isothiocyanate rifatanye n'impeta ya benzene yasimbuwe na trifluoromethyl. Ikoreshwa cyane cyane nk'igikoresho cy'ubwubatsi mu buryo butandukanye mu guhuza ibinyabuzima, bigatuma habaho imiterere y'uturemangingo n'ibikoresho bikora neza.
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![Isohoka(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacidmethyeste CAS:171489-59-1](https://cdn.globalso.com/xindaobiotech/5EVBWZZXL9LE4FA@55921.png)
Isohoka(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacidmethyeste CAS:171489-59-1
(1R, 3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid Methyl Ester, mu magambo ahinnye asobanura neza, ni igikoresho cy’ibinyabutabire kizwiho imiterere yacyo ikomeye ya molekile n’ikoreshwa ryacyo mu buvuzi. Iki kintu gihuza igice cy’imbere cya pyridoindole n’impeta ya tetrahydrofuran ivanze n’itsinda rya chloroacetyl n’igice cya 1,3-benzodioxol-5-yl, gifite imikorere ya methyl ester. Ibi bintu by’imiterere bitanga inzira zo guhindura imiterere itandukanye no gukora ubushakashatsi bwimbitse ku binyabuzima.
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Candesartan ester hagati C3 CAS:136285-65-9
Candesartan ester intermediate C3 ni ikintu cy'ingenzi mu gukora Candesartan cilexetil, umusemburo uzwi cyane wa angiotensin II receptor antagonist ukoreshwa cyane cyane mu kuvura umuvuduko ukabije w'amaraso n'indwara z'umutima. Iki kintu intermediate gikora uruhare runini mu nganda zikora imiti bitewe n'uruhare rwacyo nk'intangiriro mu gukora neza kwa Candesartan cilexetil.
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Linagliptin interMediate F CAS: 853029-57-9
Linagliptin Intermediate F ni ingenzi cyane mu gukora linagliptin, irinda dipeptidyl peptidase-4 (DPP-4) ikomeye ikoreshwa mu kuvura diyabete yo mu bwoko bwa 2. Iyi intermediate igira uruhare runini mu nganda zikora imiti bitewe n'imiterere yayo yihariye y'ibinyabutabire n'imikorere yayo. Linagliptin, izwi mu buryo bw'imiti nka (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-(2,4,5-trifluorophenyl)-1,2-dihydroquinazolin-2(3H)-one, igira ingaruka nziza ku kuvura igabanya imikorere ya enzyme ya DPP-4, bityo yongera urugero rw'imisemburo ya incretin nka GLP-1 (peptide-like glucagon-1). Ibi bituma habaho uburyo bwiza bwo kugenzura glycemic ku barwayi ba diyabete.
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Candesartan Cilexetil Impurity 8 CAS:139481-28-0
Candesartan Cilexetil Impurity 8 ni umusaruro uvuka mu gihe cyo gukora Candesartan cilexetil, umuti urwanya angiotensin II receptor antagonist ukoreshwa cyane cyane mu kuvura umuvuduko ukabije w'amaraso n'indwara z'umutima. Nubwo utifuzwa mu buryo bwa nyuma bwo gukoresha imiti, gusobanukirwa no kugenzura imiterere y'umwanda ni ingenzi cyane mu kwemeza ko ibicuruzwa bifite umutekano, imikorere myiza, n'uko bikurikiza amategeko.
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![ACID BENZOIC, 2-[[(1,1-DIMETHYLETHOXY)KABONYL]AMINO]-3-NITRO-METHYL ESTER CAS:57113-90-3](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG299.png)
ACID BENZOIC, 2-[[(1,1-DIMETHYLETHOXY)KABONYL]AMINO]-3-NITRO-METHYL ESTER CAS:57113-90-3
ACID BENZOIC, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER ni imvange y’ibinyabutabire izwi cyane kubera imiterere yayo ikomeye ya molekile n’ikoreshwa ryayo mu buvuzi. Iyi mvange ihuza ingirabuzimafatizo ya aside benzoic hamwe n’igice cya carbamate kirimo itsinda rya dimethylethoxy hamwe n’imikorere ya nitro-methyl ester, bigatuma igira uruhare runini mu bushakashatsi ku buvuzi no mu bushakashatsi ku binyabutabire bitewe n’imiterere yayo yihariye n’ibikorwa byayo mu binyabuzima.
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pyridine-3-sulfonyl chloride CAS: 16133-25-8
Pyridine-3-sulfonyl chloride ni imvange y’ibinyabutabire izwiho gukoresha mu buryo butandukanye mu gukora imvange y’ibinyabuzima no mu bushakashatsi ku miti. Iyi mvange, izwi kandi nka picolinoyl chloride, ifite core ya pyridine yasimbuwe n’itsinda rya sulfonyl chloride ku mwanya wa 3, bigatuma igira akamaro kanini kubera uburyo ikora neza kandi ishobora gukoreshwa mu buryo butandukanye bw’ibinyabutabire.
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5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile CAS:1240948-77-9
5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile ni ikinyabutabire kirangwa n'imiterere ya molekile n'ikoreshwa ryacyo mu buvuzi no mu guhuza ibinyabuzima. Iki kinyabutabire gifite ishingiro rya pyrrole risimbuwe n'itsinda rya fluorophenyl n'itsinda rya cyano mu myanya yihariye, bigatuma kiba ingenzi kubera imiterere yacyo n'ibikorwa byacyo bya biyoloji.
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Vonoprazan CAS: 881681-00-1
Vonoprazan ni ikinyabutabire cy’imiti kizwiho ubushobozi bwacyo bwo kugabanya aside yo mu gifu, kikaba gitandukanye n’ibinyabutabire gakondo bya proton pump (PPI) bitewe n’uburyo kidasanzwe cyo gukora. Iki kinyabutabire kibuza pompe ya proton H+, K+-ATPase mu turemangingo tw’igifu ku buryo bwihariye kandi bunoze, bigatuma aside igabanuka cyane kandi ihoraho.
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N-(4-CYANO-PHENYL)-GLYCINE CAS:42288-26-6
N-(4-Cyano-phenyl)-glycine ni imvange y’ibinyabutabire irangwa n’imiterere yayo ya molekile n’ikoreshwa ryayo mu nzego zitandukanye, cyane cyane mu bushakashatsi ku buvuzi n’ubushakashatsi ku binyabutabire. Iyi mvange ihuza itsinda rya phenyl n’igice cya glycine, bigatuma igira akamaro bitewe n’imiterere yayo yihariye n’ibikorwa byayo bya biyoloji.
