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Lasmiditant CAS: 439239-90-4
Lasmiditan, icuruzwa ku izina rya Reyvow, ni ikinyabutabire gishya cy’imiti cyagenewe kugabanya ibitero by’umutwe ukabije ku bantu bakuru. Ni mu itsinda ry’imiti itoranya serotonin receptor agonists, cyane cyane yibasira ubwoko bwa 5-HT1F receptor. Ubu buryo bwo gukora butandukanya Lasmiditan n’imiti gakondo ivura umutwe ukabije, kuko idatera imitsi ku barwayi, bigatuma ikoreshwa neza ku barwayi bafite ibyago byo kurwara indwara z’umutima n’imitsi.
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N-Methylcarbonyl-2-chloroacetamidrazone CAS: 155742-64-6
N-Methylcarbonyl-2-chloroacetamidrazone ni imvange y’ibinyabutabire izwiho gukoresha mu buryo butandukanye mu guhuza ibinyabuzima no guhuza imikorere yabyo. Imvange yayo ikubiyemo uburyo N-methylcarbamoyl chloride ikorana na 2-chloroacetohydrazide, bigatuma habaho imvange ifite imiterere n’imikorere itandukanye. Iyi mvange irangwa n’ubushobozi bwayo bwo gukora imiterere itandukanye y’ibinyabutabire, bigatuma igira akamaro mu bushakashatsi ku bijyanye n’imikoranire yabyo. Byongeye kandi, amatsinda yayo ya karuboni na amidrazone agira uruhare mu gukora neza no gukora neza kwabyo mu bijyanye n’imiti, ari na byo biri mu bushakashatsi bukomeje gukorwa.
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Lasmiditan HCl CAS: 613677-28-4
Lasmiditan hydrochloride (Lasmiditan HCl) ni ikinyabutabire cy’imiti kizwiho uruhare rwacyo mu kuvura indwara zo mu mutwe zikabije ku bantu bakuru. Yakozwe nk'umuti uvura serotonin receptor agonist, cyane cyane wibasira ubwoko bwa 5-HT1F receptor, Lasmiditan HCl ni intambwe ikomeye mu kuvura indwara zo mu mutwe bitewe n'uburyo ikora n'ubushobozi bwayo bwo kuvura.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS:613678-03-8
(6-Aminopyridin-2-yl) (1-methylpiperidin-4-yl)methanone, izwi kandi nka aminopyridine methylpiperidone, ni ikinyabutabire gifite ingaruka zikomeye mu bushakashatsi ku buhanga mu by'imiti n'imiti. Iki kinyabutabire cyakozwe binyuze mu gukorana kwa aside 6-aminopicolinic hamwe na 1-methylpiperidin-4-one, kigaragaza imiterere yihariye ituma gitanga ubushobozi bwo gukora imiti no gukora neza.
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(S)-(+)-3-Quinuclidinol CAS:34583-34-1
(S)-(+)-3-Quinuclidinol, izwi kandi ku izina rya quinuclidinol, ni ikintu cy'ingenzi mu bushakashatsi bwa chimie organic na farumasi bitewe n'imiterere yacyo yihariye n'uburyo ikoreshwa mu buryo butandukanye. Iki kintu cya chiral gikomoka kuri quinuclidine kandi kigaragaza imiterere yihariye ya chimie na farumasi byakuruye ibitekerezo mu nzego zitandukanye za siyansi.
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IMPAMVU ZA APREPITANT CAS: 171482-05-6
Aprepitant intermediates igira uruhare runini mu gukora imiti ya aprepitant, umuti ukomeye wa neurokinin-1 (NK1) ukoreshwa cyane cyane mu gukumira isesemi iterwa na chemotherapy (CINV). Iyi intermediates ni ingenzi mu nzira y’ubukorano y’intambwe nyinshi iganisha ku buryo bwa nyuma bwa aprepitant. Aprepitant ubwayo izwiho ubushobozi bwayo mu kuvura CINV, itanga ubutabazi bukomeye ku barwayi bakorerwa chemotherapy. Gukora aprepitant bikubiyemo intambwe nyinshi z'ingenzi, aho intermediates zikora nk'inkingi z'ingenzi zituma uyu muti w'ingenzi uvura ukorwa neza.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS:79538-29-7
2,4,6-Trifluorobenzoyl chloride, izwi kandi nka trifluorobenzoyl chloride, ni ikintu cy'ingenzi mu binyabutabire gifite agaciro gakomeye kubera uburyo gikoreshwa mu gukora ibintu bitandukanye mu buryo bw'umwimerere no mu nganda. Iyi aside 2,4,6-trifluorobenzoic ikora hifashishijwe chlorine, igaragaza imiterere yihariye y'ibinyabutabire ituma ikoreshwa mu buryo butandukanye mu nzego zitandukanye.
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4-Chloro-6-iodoquinazoline CAS:98556-31-1
4-Chloro-6-iodoquinazoline ni imvange y’ibinyabutabire ifite formula ya molekile C9H5ClIN2. Irangwa no kuba hari atome za chlorine na iyode zifatanye n’imiterere y’impeta ya quinazoline. Iyi mvange ikoreshwa cyane cyane mu bushakashatsi ku miti no mu gukora organic synthesis bitewe n’uko ishobora gukoreshwa mu gukora imiti mishya n’izindi molekile zikora ku buzima bw’umuntu.
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(R)-3-Quinuclinol CAS: 25333-42-0
(R)-3-Quinuclinol, izwi kandi nka quinuclidinol, ni ikintu gikomeye mu bushakashatsi bwa chimie organic na farumasi bitewe n'imiterere yacyo yihariye n'uburyo ikoreshwa mu buryo butandukanye. Iki kintu cya chiral gikomoka kuri quinuclidine kandi kigaragaza imiterere yihariye ya chimie na farumasi byakuruye ibitekerezo mu nzego zitandukanye za siyansi.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
Ikinyabutabire (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate ni molekile y’ibinyabuzima ifite imiterere yihariye n’imiterere y’imiti. Ni mu bwoko bwa morpholine bw’ibinyabutabire, bikunze gukoreshwa mu buvuzi bitewe n’ibikorwa byabyo bitandukanye bya biyoloji.
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![(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine ni ikinyabutabire kizwiho gukoresha mu buryo butandukanye mu gukora organic synthesis no mu buvuzi. Kivangwa binyuze mu gukora kwa (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone hamwe na ammonia cyangwa amine, iki kinyabutabire gifite imiterere yihariye ituma imikorere yacyo itandukanye ndetse n'imikorere ishobora gukorwa mu buvuzi.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS:608142-27-4
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine ni ikinyabutabire kizwiho ikoreshwa mu buryo butandukanye mu gukora organic synthesis no mu buvuzi. Kivangwa binyuze mu gukora kwa 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone hamwe na ammonia cyangwa amine, iki kinyabutabire kigaragaza imiterere yihariye ituma imikorere yacyo irushaho kuba myiza ndetse n'imikorere ishobora gukorwa mu buvuzi.
