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(S)-4-benzyl-2-oxazolidinone CAS:90719-32-7
(S)-4-benzyl-2-oxazolidinone ni ikinyabutabire kirangwa n'itsinda rya benzyl rifatanye n'impeta ya oxazolidinone. Ikoreshwa mu bushakashatsi ku binyabutabire n'imiti bitewe n'imiterere yayo yihariye y'ibinyabutabire.
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Lapatinib CAS: 231277-92-2
Lapatinib ni ikinyabutabire cy’imiti gifite formula ya molekile C29H26ClFN4O4S. Ni mu itsinda ry’imiti ibuza tyrosine kinase kandi ikoreshwa cyane cyane mu kuvura ubwoko bumwe na bumwe bwa kanseri, cyane cyane kanseri y’ibere. Lapatinib ikora mu gukumira tyrosine kinases EGFR (receptor y’ingirabuzimafatizo zo gukura kwa epidermal) na HER2 (receptor y’ingirabuzimafatizo zo gukura kwa epidermal 2 y’umuntu), bigira uruhare mu gutuma uturemangingo twa kanseri twiyongera kandi turushaho kwiyongera.
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(R)-4-benzyl-2-oxazolidinone CAS:102029-44-7
(R)-4-benzyl-2-oxazolidinone ni ikinyabutabire gifite imiterere ya molekile irimo itsinda rya benzyl rifatanye n'impeta ya oxazolidinone. Ikoreshwa mu bushakashatsi bwa biochemical na farumasi bitewe n'imiterere yayo yihariye ya shimi.
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(5-Thiazolyl)methyl-(4-nitrophenyl)carbonate (NCT) CAS:144163-97-3
NCT, cyangwa (5-Thiazolyl)methyl- (4-nitrophenyl)carbonate, ni ikinyabutabire gikoreshwa mu bushakashatsi bwa biochemical na farumasi. Ifite imiterere yihariye ya molekile ituma ikoreshwa mu bushakashatsi bujyanye no kuvumbura no guteza imbere imiti.
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Methyl phenylacetate CAS: 101-41-7
Methyl phenylacetate ni ikinyabutabire kirangwa n'itsinda rya phenyl rifatanye n'igice cya acetate binyuze mu itsinda rya methyl. Ikoreshwa mu bikorwa bitandukanye by'inganda n'ubushakashatsi bitewe n'imiterere yayo yihariye ya shimi.
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(S,Z)-5-Amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one(DAH-II) CAS:156732-13-7
DAH-II, cyangwa (S,Z)-5-Amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one, ni ikinyabutabire gikoreshwa mu bushakashatsi ku binyabuzima n'imiti. Gifite imiterere yihariye ya molekile ituma kigira akamaro mu bushakashatsi bujyanye no kuvumbura no guteza imbere imiti.
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Ethyl phenylacetate CAS: 101-97-3
Ethyl phenylacetate ni ikinyabutabire kirangwa n'itsinda rya phenyl rifatanye n'igice cya acetate binyuze mu itsinda rya ethyl. Iboneka mu bikorwa bitandukanye by'inganda n'ubushakashatsi bitewe n'imiterere yayo yihariye y'ibinyabutabire.
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2-Formylfuran-5-boronike aside CAS: 27329-70-0
2-Aside Formylfuran-5-boronic ni imvange y’ibinyabutabire irangwa n’itsinda ryayo rya aside boronic ifatanye n’impeta ya furan ifite formyl substituent. Ikoreshwa mu guhuza organic nk'igikoresho cy’ubwubatsi gifite ubushobozi bwo gukora esters za boronate zihamye ndetse no gukora reactions mu guhuza. Imiterere y’iyi mvange yorohereza kuyihuza mu buryo butandukanye bwa molekile, bigatuma igira akamaro mu bushakashatsi ku miti no mu buhinzi.
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1,2,3-triacetyl-5-deoxy-β-D-Ribose CAS: 62211-93-2
1,2,3-Triacetyl-5-deoxy-β-D-ribose ni imvange y’ibinyabutabire ifite formula ya molekile C14H18O7. Irangwa n’imiterere y’isukari ya ribose ifite amatsinda atatu ya acetyl afatanye n’amatsinda ya hydroxyl ku mwanya wa 1, 2, na 3. Iyi mvange ni ingenzi mu bushakashatsi bwa shimi y’ibinyabuzima n’imiti bitewe n’akamaro kayo nk’itsinda ririnda ribose mu gukora nucleoside ndetse no kuba intandaro mu gutegura analogues za nucleotide.
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(2S,3S,5S)-5-(Tert-butyloxycarbonyl)amino-2-amino-3-hydroxy-1,6-diphenyl hexane (BDH Pure) CAS:144163-85-9
BDH Pure, cyangwa (2S,3S,5S)-5-(tert-butyloxycarbonyl)amino-2-amino-3-hydroxy-1,6-diphenyl hexane, ni ikintu gikoreshwa mu bushakashatsi ku binyabuzima n'imiti. Gifite imiterere yihariye ya molekile igira uruhare mu ikoreshwa ryayo mu butabire bwa peptide no mu iterambere ry'imiti.
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2′,3′-Di-O-acetyl-5′-deoxy-5-fuluro-D-cytidine CAS:161599-46-8
2′,3′-Di-O-acetyl-5′-deoxy-5-fluoro-D-cytidine ni imvange y’ibinyabutabire ifite formula ya molekile C13H16FN3O6. Irangwa n’imvange ya cytidine ifite amatsinda ya acetyl afatanye n’imyanya ya 2′ na 3′ hamwe n’isimbuza rya fluorine ku mwanya wa 5′ w’isukari ya ribose. Iyi mvange ni ingenzi mu bushakashatsi ku binyabutabire bya nucleoside no mu buvuzi bw’imiti bitewe n’uko ishobora gukoreshwa mu guteza imbere imiti irwanya kanseri no kurwanya virusi.
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Trans-1,2-diaminocyclohexane CAS: 1121-22-8
Trans-1,2-diaminocyclohexane ni imvange y’ibinyabutabire ifite formula ya molekile C6H14N2. Igizwe n’impeta ya cyclohexane ifite amatsinda abiri ya amino (-NH2) afatanye na atome za karuboni zegeranye mu buryo bwa trans. Iyi mvange irazwi cyane mu bushakashatsi bwa shimi y’ibinyabuzima n’imiti bitewe n’uburyo ikoreshwa mu gushushanya ligand mu gukata ibyuma ndetse no nk’inkingi y’ubwubatsi bw’ibinyabutabire bikora ku binyabuzima.
