Boc-Phe-ONp CAS: 7536-56-0

Boc-Phe-ONp igira uruhare runini mu gukora peptide, cyane cyane mu gukora peptide ishingiye ku gipimo cya solution-phase na peptide ishingiye ku gipimo cya sol-phase (SPPS). Nk'ikintu kirinzwe kivamo aside amine, ikora nk'ingenzi mu kubaka ibisigazwa bya phenylalanine mu miterere ya peptide. Muri SPPS, Boc-Phe-ONp ikoreshwa mu kwinjiza ibice bya phenylalanine mu buryo bwihariye mu gihe cyo guteranya iminyururu ya peptide ku nkunga zikomeye, mu gihe mu gukora peptide ishingiye ku gipimo, ituma habaho iminyururu ya peptide mu miterere ishingiye ku gisubizo. Abashakashatsi n'abahanga mu by'imiti bakoresha Boc-Phe-ONp kugira ngo bakore peptides zihariye zifite imiterere yihariye ya aside amine zigenewe isuzuma ry'ibinyabuzima, inyigo z'imiterere, n'iterambere ry'imiti. Binyuze mu gukoresha reactivity y'itsinda rya 4-nitrophenyl ester, bashobora kugera ku guhuza neza n'amatsinda ya amine, biganisha ku kurengerwa kw'iminyururu ya peptide no gukora imiterere itandukanye ya peptide. Uburyo Boc-Phe-ONp ikora neza butuma iba igikoresho cy'ingenzi mu nzego zitandukanye nka biochimie, farumasi, na biotechnology. Kuba ihura na protocole zisanzwe zo gukora peptide, umusaruro mwinshi, n'imikorere yizewe bigira uruhare mu ikoreshwa ryayo mu nzego z'ubushakashatsi n'inganda. Byaba bikoreshwa mu bushakashatsi bw'ibanze cyangwa mu gushaka imiti, Boc-Phe-ONp yorohereza ikorwa rya peptides zishyigikira iterambere ry'ingenzi mu buhanga mu by'ubuvuzi no mu guhanga udushya mu buvuzi.