Boc-D-Phe-ONp CAS:16195-70-9

Boc-D-Phe-ONp igira uruhare runini mu gukora peptide, cyane cyane mu gukora peptide y’igice cya solid-phase (SPPS) no gukora peptide y’igice cya solution. Nk’ikivange cy’aside amine kirinzwe, byoroshya kwinjiza ibisigazwa bya D-phenylalanine mu byiciro bya peptide. Muri SPPS, Boc-D-Phe-ONp ikoreshwa mu gushyiramo ibice bya D-phenylalanine mu buryo bwihariye mu gihe cyo guteranya iminyururu ya peptide ku nkunga zikomeye, mu gihe mu gukora peptide y’igice cya solution, ituma habaho iminyururu ya peptide mu bikorwa bishingiye ku bushobozi. Abashakashatsi n’abahanga mu by’imiti bakoresha Boc-D-Phe-ONp kugira ngo bakore peptide zihariye zifite iminyururu yihariye ya aside D-amino zikozwe neza mu gusuzuma ibinyabuzima, ubushakashatsi ku miterere, no guteza imbere imiti. Bikoresheje uburyo itsinda rya 4-nitrophenyl ester rikora, bashobora kugera ku guhuza neza n’amatsinda ya amino, biganisha ku kurengerwa kw’iminyururu ya peptide no gukora imiterere itandukanye ya peptide. Kuba Boc-D-Phe-ONp ikora ibintu byinshi bituma iba igikoresho cy'agaciro mu nzego zitandukanye nko mu buvuzi bwa biochimie, mu buvuzi bw'imiti, no mu buvuzi bwa biotechnology. Ihuye na gahunda zisanzwe zo gukora peptide, umusaruro mwinshi, n'imikorere yizewe bigira uruhare mu ikoreshwa ryayo mu nzego z'ubushakashatsi n'inganda. Yaba ikoreshwa mu bushakashatsi bw'ibanze cyangwa mu bushakashatsi bw'imiti, Boc-D-Phe-ONp yorohereza ikorwa rya peptides zishyigikira iterambere ry'ingenzi mu buvuzi bw'ubuvuzi no guhanga udushya mu buvuzi.