Boc-Orn(2-Cl-Z)-OH CAS:118554-00-0

Boc-Orn (2-Cl-Z)-OH ikoreshwa cyane mu gukora peptide ikoze mu cyiciro gikomeye kugira ngo ikore peptide zakozwe ku giti cyazo zifite uruhererekane n'imikorere yihariye. Ikoreshwa ryayo ryemerera kwinjiza ibisigazwa bya ornithine mu buryo bugenzurwa kandi butoranijwe, byoroshya ikorwa rya peptide zikomeye zagenewe gukoreshwa mu buryo butandukanye, harimo kuvumbura imiti no gukora poroteyine. Mu bijyanye no guhuza ibinyabuzima n'ibinyabuzima, Boc-Orn (2-Cl-Z)-OH ikora nk'inkingi ikomeye yo gukora peptide zikora ku mubiri, imashini zigaragaza amazina, n'imiti ishingiye kuri peptide. Guhindura neza peptide na poroteyine hakoreshejwe Boc-Orn (2-Cl-Z)-OH bituma habaho iterambere rya molekile zikora byinshi zifite ubushobozi bwo guhagarara neza, ubushobozi bwo gushushanya, cyangwa ubushobozi bwo gufata amashusho, zishyigikira ikoreshwa ry'ubuvuzi butandukanye. Byongeye kandi, mu guteza imbere imiti, Boc-Orn (2-Cl-Z)-OH igira uruhare runini mu gukora peptide zahinduwe na conjugates zifite imiterere myiza ya pharmacokinetic n'ibikorwa bya biyoloji. Izi mpinduka zikozwe mu buryo bwihariye zishobora kongera imikorere, guhitamo, no gutanga imiti ishingiye kuri peptide, bigafasha mu iterambere mu buvuzi bwihariye no mu buvuzi bunoze. Muri make, kuba Boc-Orn (2-Cl-Z)-OH yari yizewe kandi ikora neza mu gukora peptide no guhuza ibinyabuzima bituma iba igikoresho cy'ingirakamaro mu guteza imbere ubushakashatsi mu kuvumbura imiti, ibinyabuzima by'ibinyabutabire, na proteomics, bitanga amahirwe atandukanye yo guteza imbere uburyo bushya bwo gukoresha imiti.