γ-L-Glutamyl-3-carboxy-4-nitroanilide, umunyu wa monoammonium CAS: 63699-78-5

Umunyu wa monoammonium γ-L-Glutamyl-3-carboxy-4-nitroanilide ni substrate ikoreshwa cyane mu isuzuma rya biochemical kugira ngo hamenyekane kandi hapimwe imikorere ya enzyme γ-glutamyl transpeptidase (GGT). GGT ni enzyme iboneka mu ngingo zitandukanye, harimo umwijima, impyiko na pancreas. Igira uruhare mu gusenyuka no guhindagurika kwa glutathione, antioxidant y'ingenzi mu turemangingo.

Iyi mvange ihindurwamo GGT ikaba iy'umuhondo, ishobora gupimwa hakoreshejwe spectrophotometric ku rugero runaka rw'uburebure. Ubukana bw'ibara bujyanye neza n'imikorere ya GGT mu gipimo. Ibi bituma hapimwa urugero rw'imikorere ya GGT, bishobora gufasha mu gusuzuma imikorere y'umwijima no gusuzuma indwara z'umwijima.

Gukoresha γ-L-Glutamyl-3-carboxy-4-nitroanilide, umunyu wa monoammonium mu bipimo bya GGT ni ingirakamaro mu bintu bitandukanye, harimo gusuzuma indwara, ubushakashatsi, no guteza imbere imiti. Bifasha gukurikirana imikorere ya GGT mu barwayi, bigafasha mu kumenya no gusuzuma indwara z'umwijima nk'indwara z'umwijima ziterwa n'inzoga, kanseri y'umwijima, n'ibyangiritse by'umwijima biterwa n'imiti.