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ibicuruzwa

Ibicuruzwa

β-Nicotinamide Mononucleotide CAS: 1094-61-7

Nikotinamide mononucleotide (NMN), umusaruro wibisubizo bya NAMPT hamwe ningenzi hagati ya NAD + hagati, bivugurura kutihanganira glucose mugusubiza urwego rwa NAD + mumbeba za T2D zatewe na HFD.NMN kandi yongerera imbaraga insuline ya insuline kandi igarura imvugo ya gene ijyanye na stress ya okiside, igisubizo kibabaza, hamwe nigitekerezo cya circadian, igice binyuze muri SIRT1.NMN ikoreshwa mukwiga motifs muri RNA aptamers hamwe na gahunda yo gukora ribozyme irimo β-nicotinamide mononucleotide (β-NMN) -bikora RNA ibice.


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Gushyira mu bikorwa n'ingaruka

β-Nicotinamide mononucleotide (NMN) ikoreshwa mukwiga motif ihuza muri RNA aptamers hamwe na gahunda yo gukora ribozyme irimo β-nicotinamide mononucleotide (β-NMN) -bikora RNA ibice.NMN ni nucleotide ikomoka kuri ribose na nicotinamide.Niacinamide (nicotinamide,) ni inkomoko ya vitamine B3, izwi kandi ku izina rya niacin.) Nka biohimiki ibanziriza NAD +, irashobora kuba ingirakamaro mu gukumira pellagra.
β-Nicotinamide mononucleotide ni intera hagati ya biosynthesis ya nicotinamide adenine dinucleotide (NAD +).Nicotinamide fosiforiibosyltransferase (Nampt) itera ubukana bwa nicotinamide hamwe na 5-fosifori-1-pyrophosifate kugirango itange β-NMN, nyuma ihinduka NAD + na β-NMN adenyltransferase. Muri 50-100 μM, β-NMN yakoreshejwe mu kuzamura NAD biosynthesis na glucose-iterwa na insuline isohoka muri Nampt +/- imbeba yindwara ya metabolike, byerekana uruhare rwa Nampt mumikorere ya selile.

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Gupakira ibicuruzwa:

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Amakuru yinyongera:

Ibigize C11H15N2O8P
Suzuma 99%
Kugaragara Ifu yera
URUBANZA No. 1094-61-7
Gupakira 25KG
Ubuzima bwa Shelf Imyaka 2
Ububiko Ubike ahantu hakonje kandi humye
Icyemezo ISO.

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