β-Nicotinamide Mononucleotide CAS: 1094-61-7

Nicotinamide mononucleotide (NMN), umusaruro wa NAMPT reaction ikaba n'igice cy'ingenzi cya NAD+ intermediate, yoroshya ukwihanganira isukari binyuze mu kugarura urugero rwa NAD+ mu mbeba za T2D ziterwa na HFD. NMN kandi yongera ubushobozi bwo kumva insuline mu mwijima kandi igasubizaho imiterere ya gene ijyanye n'umuvuduko wa oxidative, igisubizo cy'ububyimbirwe, n'imikorere ya circadian, igice kimwe binyuze mu gukora kwa SIRT1. NMN ikoreshwa mu kwiga uburyo bwo gufatanya muri aptamers za RNA na ribozyme processes zirimo ibice bya RNA bikoreshwa na β-nicotinamide mononucleotide (β-NMN).

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β-Nicotinamide mononucleotide (NMN) ikoreshwa mu kwiga uburyo bwo gufatanya muri aptamers za RNA n'ibikorwa byo gukora ribozyme birimo ibice bya RNA bya β-nicotinamide mononucleotide (β-NMN). NMN ni nucleotide ikomoka kuri ribose na nicotinamide. Niacinamide (nicotinamide,) ni ikomoka kuri vitamine B3, izwi kandi nka niacin.) Nk'ikintu gitanga ubuziranenge bwa biochemical cya NAD+, gishobora kugira akamaro mu gukumira pellagra.
β-Nicotinamide mononucleotide ni urwego ruciriritse mu gukora nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) itera imbaraga mu gukora nicotinamide hamwe na 5-phosphoribosyl-1-pyrophosphate kugira ngo ikore β-NMN, nyuma igahindurwa NAD+ na β-NMN adenyltransferase. Kuri 50-100 μM, β-NMN yakoreshejwe mu kongera gukora NAD no gukora insuline ikomoka kuri glucose mu buryo bwa Nampt+/- bw'indwara ya metabolike, bigaragaza uruhare rwa Nampt mu mikorere y'uturemangingo twa β.

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Amakuru y'inyongera:

Imiterere	C11H15N2O8P
Isuzuma	99%
Isura	Ifu y'umweru
Nimero ya CAS	1094-61-7
Gupakira	25KG
Igihe cyo kuruhuka	Imyaka 2
Ububiko	Bika ahantu hakonje kandi humutse
Icyemezo	ISO.