Uridine-5′-diphosphoglucuronic aside trisodium umunyu CAS: 63700-19-6

Gukuraho uburozi: Aside ya UDP-glucuronic ni ingenzi mu bigize uburyo bwo guhindura imiterere y’ibinyabuzima mu cyiciro cya kabiri cya xenobiotics n’ibintu bikomoka ku mubiri. Ikora nk'intangiriro yo gukora glucuronides, ari zo ngirabuzimafatizo zishobora gushonga cyane mu mazi zishobora gukurwa mu mubiri byoroshye. Iyi nzira yo gukuraho uburozi ifasha mu gukuraho no gukuraho ibintu bishobora kwangiza umubiri, nk'imiti, uburozi bukomoka ku bidukikije, n'ibindi bintu bishobora gutera imihindagurikire y'ikirere.

Ihindagurika ry'imiti: Imiti myinshi ikorerwa glucuronidation, inzira aho aside UDP-glucuronic ihurira n'umuti, bigatuma habaho metabolite ya glucuronide. Iyi reaction ya glucuronidation ikunze kongera uburyo imiti iva mu mubiri kandi ikayorohereza gusohoka kwayo mu nkari cyangwa mu nda. UDP-glucuronic acid trisodium salt ikoreshwa kenshi mu bushakashatsi bugamije gusuzuma imikorere y'imiti n'imiti.

Igikoresho cy'ubushakashatsi: UDP-glucuronic acid Umunyu wa trisodium ukoreshwa cyane nk'igikoresho cy'ubushakashatsi mu bushakashatsi butandukanye bujyanye n'imikorere y'imiti, enzymes, na toxicology. Utanga isoko ya aside UDP-glucuronic yo kugerageza mu buryo bwa vitro kandi ugafasha abashakashatsi gukora iperereza ku ngaruka za glucuronization ku isukurwa ry'imiti, ku kuboneka kwayo, ndetse n'imikoranire ishobora hagati y'imiti n'imiti.

Glycosylation: Aside ya UDP-glucuronic nayo igira uruhare mu mikorere ya glycosylation, aho ikora nk'umuterankunga w'ibice bya aside glucuronic mu gukora glycosaminoglycans (GAGs) na proteoglycans. Izi molekyuli zifite uruhare runini mu mikorere itandukanye ya biyoloji, harimo gufatana kw'uturemangingo, gukora matrix yo hanze y'umubiri, no gutanga ibimenyetso.