Tos-Gly-OSu CAS: 68385-26-2

Tos-Gly-OSu igira uruhare runini mu gukora peptide nk'ikintu cy'ingenzi mu gukora neza kw'amatsinda ya amine. Kuba hari itsinda rya tosyl n'imikorere ya NHS bituma habaho uburyo bwo guhuza ibintu, bigatuma peptide zirimo glycine zihuzwa n'izindi molekyuli cyangwa ubuso mu buryo bugenzurwa. Iki kintu gifite akamaro mu gukora peptide conjugates zifite imiterere yihariye nko kunoza ubushobozi bwo guhagarara neza, gushonga, cyangwa ubushobozi bwo guhuza ibintu. Mu guteza imbere imiti, Tos-Gly-OSu ishobora gukoreshwa mu gukora peptide-drug conjugates, bishobora gutuma habaho imikorere myiza mu kuvura, gutanga imiti ku buryo bugamije, cyangwa gukoresha mu gusuzuma. Uretse uruhare rwayo mu gukora peptide, Tos-Gly-OSu ikoreshwa mu bushakashatsi bwa poroteyine n'ubushakashatsi bwa biochemical, aho ishobora gukoreshwa mu guhindura poroteyine mu buryo bwihariye, gukora isomero rya peptide, cyangwa gukora ku buso mu bipimo bitandukanye bya bioanalytical. Uburyo ikora neza kandi ihuye n'imiterere itandukanye y'igerageza bituma iba igice cy'ingenzi mu gusesengura ingorane za sisitemu za biyoloji no guteza imbere uburyo bwo kuvura indwara zitandukanye. Muri make, Tos-Gly-OSu ni igikoresho cy'agaciro ku bashakashatsi mu bijyanye no gukora peptide, guteza imbere imiti, n'ubushakashatsi ku binyabuzima, itanga ubushobozi bwo guhindura peptide na poroteyine bifite imiterere n'imikorere yihariye, bityo bigatanga umusanzu mu iterambere mu buvuzi, ikoranabuhanga rya bio, n'ubuhanga bwo guhuza bio.