Tert-Butyl 4-(6-Bromo-[1,2,4]Triazolo[1,5-A]Pyridin-2-Yl)Piperidine-1-Karuboksilate CAS:1422344-42-0

Tert-butyl 4-(6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)piperidine-1-carboxylate igira uruhare runini nk'igice cy'ingenzi mu gukora imvange y'ibintu bigoye kandi bikora neza hamwe n'ikoreshwa ry'imiti. Kwinjizwa kwayo mu buryo bwa molekile bituma abashakashatsi bashobora gushakisha imiti mishya yibanda ku bice by'ubuvuzi nk'indwara z'imitsi, kanseri, cyangwa indwara zandura. Kuba iri mu itsinda rya triazolopyridine bitanga uburyo bwihariye bwo gukora no gufata imiti, bigatuma igira akamaro mu bushakashatsi ku buhanga bwa chimie mu buvuzi. Mu gushaka imiti, iyi mvange ishobora kuba intangiriro yo gushushanya imiti ishobora kuba ikoreshwa, ikoresheje imiterere yayo kugira ngo ihindure imikorere y'ibinyabuzima n'imiterere ya pharmacokinetic. Byongeye kandi, itsinda rya tert-butyl ritanga imbogamizi za steric, rigira ingaruka ku mikoranire y'iyi mvange n'intego za biyoloji kandi rigatanga umusanzu mu gushakisha uburyo bushya bwo kuvura. Byongeye kandi, mu nzego z'ubushakashatsi n'inganda, abashakashatsi bashobora gukoresha iyi mvange mu gutegura amasomero y'ibintu bitandukanye bikomoka ku miti kugira ngo bakore ubushakashatsi ku miterere n'imikorere, byorohereze kumenya imvange y'ibikomoka ku misemburo ifite ingaruka nziza ku biyoloji. Uruhare rwayo mu guhuza imiti rugera no ku gukora imiti ihuza imiti n’iterambere ry’uburyo bushya bwo gukora imiti, igaragaza akamaro kayo mu nzego za siyansi. Muri rusange, tert-butyl 4-(6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)piperidine-1-carboxylate igira uruhare runini mu gushaka kuvumbura imiti igezweho n’ubushakashatsi ku miti, itanga urubuga rwo guteza imbere molekile zitandukanye zikora mu buzima n’imiti ihuza imiti.