Sirolimus CAS: 53123-88-9

Ubudahangarwa bw'umubiri: Sirolimus ikoreshwa mu gukumira kwangwa kw'ingingo nyuma yo guterwa impyiko. Akenshi itangwa hamwe n'indi miti igabanya ubudahangarwa bw'umubiri kugira ngo igabanye ibyago byo kwangwa no kunoza ubuzima bw'impyiko. Ubwikorezi bw'imitsi yo mu mutima: Mu buvuzi bw'indwara z'umutima, sirolimus ikoreshwa mu miti igabanya ububabare bw'imitsi yo mu mutwe kugira ngo hirindwe ko imitsi yo mu mutwe yongera kugabanuka (restenosis) nyuma yo guterwa angioplasty, bifasha mu kubungabunga uburyo imitsi yo mu mutwe ikora kandi bigabanye gukenera imiti isubiramo. Kuvura Lymphangioleiomyomatosis (LAM): Sirolimus yemejwe mu kuvura LAM, indwara idakunze kugaragara mu bihaha, kugira ngo inoze imikorere y'ibihaha no kugabanya iterambere ry'indwara. Ubuvuzi bwa kanseri: Ikoreshwa mu kuvura ubwoko bumwe na bumwe bwa kanseri, harimo kanseri y'impyiko n'abagore bamaze gucura bafite kanseri y'ibere ikomeye, igaragaza ingaruka zo kurwanya kwangirika kw'umubiri. Indwara z'uruhu: Sirolimus yasuzumwe ku bushobozi bwayo mu kuvura indwara zitandukanye z'uruhu nka psoriasis, dermatitis ya atopic, na angiofibromas zijyanye na tuberous sclerosis complex. Gutera Imitsi y'amaraso: Mu kubaga imitsi y'amaraso, uduce duto twa sirolimus dukoreshwa mu gukumira hyperplasia y'imbere no guteza imbere uburyo bwo kongera imitsi y'amaraso mu gihe kirekire. Ubuvuzi bw'ubushakashatsi: Ubushakashatsi burakomeje ku ikoreshwa rya sirolimus mu ndwara ziterwa n'umubiri, nka lupus erythematosus, no mu rwego rw'ubuvuzi bwo kuvugurura no gukora ingirabuzima fatizo. Muri make, sirolimus igira uruhare runini mu buvuzi bwo gutera imbata, indwara z'umutima, kanseri, n'ibindi bice bitandukanye by'ubuvuzi bitewe n'ubushobozi bwayo bwo kugabanya ubudahangarwa bw'umubiri no kurwanya ikwirakwira ry'imitsi, bigira uruhare mu kunoza umusaruro w'abarwayi no guteza imbere ubuvuzi.