Simvastatin CAS: 79902-63-9 Utanga ibicuruzwa

Simvastatin ni kimwe cya kabiri cyogukora, hydrophobique irenze gato, analogue ya lovastatin.Kimwe na lovastatine, simvastatin ni inhibitori ya HMG-CoA reductase kandi ikoreshwa mubuvuzi kugirango igabanye cholesterol ya LDL.Vuba aha, statin zahindutse ingirakamaro yibinyabuzima muri biologiya selile.Uruhare rwabo mubikorwa byinshi rushobora guhuzwa nuburyo bwabo bwibanze bwibikorwa, nyamara, uburyo bwibikorwa byizindi ngaruka nyinshi ntibigaragara.Simvastatin ni inzitizi yihariye yo kugabanya HMG-CoA reductase, enzyme itera ihinduka rya HMG-CoA to mevalonate, intambwe yambere muri cholesterol biosynthesis.Ikoreshwa mu kuvura hypercholesterolemia, kuko igabanya urugero rwa lipoproteine ​​nkeya na triglyceride, kandi ikazamura urugero rwa lipoproteine.