(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine CAS:132335-44-5

(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine ni imvange ya chiral ifite akamaro kanini mu buvuzi. Iri mu itsinda ry’abarwanya β-adrenergic receptor, bazwi cyane nka beta-blockers. Iyi mvange igaragaza imiterere yihariye hamwe n’itsinda rya thienyl n’ikigo cya chiral gikora hydroxy, bitanga ibikorwa bitandukanye bya biyoloji. Beta-blockers nka (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine zikoreshwa cyane mu kuvura indwara z’umutima n’imitsi, harimo umuvuduko ukabije w’amaraso, angina, na arrhythmias, binyuze mu kubuza ingaruka za adrenaline ku mvange za beta mu mutima no mu mitsi y’amaraso. Chirality y’iyi mvange ni ingenzi kuko enantiomers zishobora kugaragaza ingaruka zitandukanye mu buvuzi bitewe n’imikoranire n’imyunyungugu runaka mu mubiri.

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Imikoreshereze n'ingaruka:

Gutunganya no kwiga (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine byakuruye ubushake mu bushakashatsi ku miti n'ubutabire. Gutunganya iyi miti mu buryo bwa enantioselective biragoye ariko ni ingenzi kugira ngo haboneke enantiomere nziza zo kwiga imikorere yayo mu by'imiti. Abashakashatsi bakoze inzira zitandukanye zo gukora hakoreshejwe imiti igabanya ubukana bwa chiral cyangwa catalysts zitangana kugira ngo haboneke enantiomere yifuza. Ubushakashatsi bwagaragaje ko (S)-enantiomere ya beta-blockers nka (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine ishobora kugaragaza ubufatanye n'uburyo bwo guhitamo beta-adrenergic receptors ugereranije na (R)-enantiomere, bigatuma iba umuti mwiza wo gukomeza gutera imbere. Ubushakashatsi bwiyongereye ku miterere y'imiti n'ubushobozi bwo kuvura bwa (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine ni ngombwa kugira ngo harebwe imikorere yayo n'umutekano wayo mu buvuzi. Gusobanukirwa isano iri hagati y’imiterere n’imikorere y’iyi mvange n’imikorere yayo na za receptor za beta bishobora gutuma habaho beta-blockers nshya zifite umusaruro mwiza mu kuvura no kugabanya ingaruka mbi. Muri rusange, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine ni ikintu cy’agaciro mu rwego rw’ubushakashatsi mu by’imiti, gitanga ubumenyi ku miterere n’iterambere ry’imiti y’umutima n’imitsi ifite imiterere myiza mu by’imiti.

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Amakuru y'inyongera:

Imiterere	C9H15NOS
Isuzuma	99%
Isura	ifu y'umweru
Nimero ya CAS	132335-44-5
Gupakira	Bito kandi byinshi
Igihe cyo kuruhuka	Imyaka 2
Ububiko	Bika ahantu hakonje kandi humutse
Icyemezo	ISO.