PUROMYCIN DIHYDROCHLORIDE CAS:58-58-2

Ingaruka ku gukora poroteyine: Puromycin isa na aminoacyl-tRNA ya 3' kandi ishobora kwinjira mu gace ka A ka ribosomes mu gihe cyo guhinduranya. Iyo imaze gushyirwamo, ituma poroteyine ihagarara vuba, bigatuma polypeptides zagabanutse. Ibi bituma puromycin iba igikoresho cy'ingirakamaro cyo kwiga gukora poroteyine n'umuvuduko w'ihindagurika ry'uturemangingo.

Ikimenyetso cyo guhitamo: Puromycin ikunze gukoreshwa nk'ikimenyetso cyo guhitamo mu bushakashatsi bw'ubuhanga mu by'uturemangingo. Uturemangingo twahinduwe cyangwa twahinduwe neza hamwe na gene ikenewe cyangwa impinduka mu by'uturemangingo turengerwa na puromycin binyuze mu gushyiramo gene yo kurwanya puromycin. Kongeramo puromycin mu mikurire y'uturemangingo bihitamo gusa uturemangingo tugaragaza gene yo kurwanya, bigatuma uturemangingo twahinduwe mu by'uturemangingo twitaruye kandi tugakwirakwira.

Isesengura ry’imikoranire ya poroteyine na poroteyine: Puromycin ishobora guhuzwa n’utumenyetso twihariye twa affinity cyangwa antibodies kugira ngo yige imikoranire ya poroteyine na poroteyine. Mu guhuza poroteyine zikorana na puromycin, birashoboka gushimangira no gutandukanya izi poroteyine kugira ngo hakorwe isesengura rirambuye.

Inyigo ku kwiyongera kwa virusi: Puromycin ishobora gukoreshwa mu kwiga kwiyongera kwa virusi mu mikurire y'uturemangingo. Mu kongeramo puromycin mu turemangingo twanduye virusi, poroteyine nshya ya virusi ishobora guhagarikwa, bigatuma abashakashatsi basuzuma uruhare rwa poroteyine runaka za virusi mu mikurire y'uturemangingo..