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Semaglutide CAS: 910463-68-2 Utanga ibicuruzwa
Semaglutide ni imiti irwanya diyabete igurishwa ku mazina nka Ozempic, Wegovy, na Rybelsus.Ikoreshwa mu kuvura diyabete yo mu bwoko bwa 2 no gucunga ibiro bidakira.Imiti ikora isa na glucagon yumuntu nka peptide-1 (GLP-1) mukongera insuline ya insuline, bigatuma habaho isukari ya metabolisme.Ikwirakwizwa nk'inshinge zapimwe munsi yikaramu yuzuye, cyangwa nkuburyo bwo munwa.Kimwe mu byiza byacyo kuruta indi miti igabanya ubukana ni uko ifite igihe kirekire cyo gukora, bityo, inshinge imwe mu cyumweru irahagije.
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Solifenacin Yatsindiye CAS: 242478-38-2 Utanga ibicuruzwa
Solifenacin succinate ni imiti igabanya ubukana ikoreshwa mu kuvura uruhago rudasanzwe rutera ibimenyetso byerekana inshuro nyinshi, byihutirwa, cyangwa kutanyurwa. Solifenacin ni antagonist ya M3 ya muscarinic antagonist yakozwe kandi yatangijwe mu kuvura uruhago rukabije (pollakiuria) mu Burayi.Kwakira M3 byagize uruhare mu kugabanuka kw'imitsi yoroheje y'imitsi y'uruhago, kandi M2 yakira na bo bakekwaho kugira uruhare kubera ubwiganze bwabo mu mitsi ya detrusor.
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N-Acetyl-L-Arginine CAS: 155-84-0 Utanga ibicuruzwa
N-Acetyl-L-Arginineni aside amine idakenewe kubantu bakuru, ariko ikorwa buhoro buhoro mumubiri.Ni aside amine yingenzi kubana bato nabana bato, kandi igira ingaruka mbi.Ihari mubwinshi muri protamine, nibindi, kandi nuburyo bwibanze bwa poroteyine zitandukanye, kandi ibaho cyane.Mubihe bisanzwe, umubiri ubwawo urashobora gutanga L-arginine ihagije.
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L-Citrulline CAS: 372-75-8 Utanga ibicuruzwa
L-citrulline ni L-enantiomer ya citrulline.Ifite uruhare nka EC 1.14.13.39 (nitric oxide synthase) inhibitor, imiti ikingira, intungamubiri, micronutrient, metabolite yumuntu, metabolite ya Escherichia coli metabolite, Saccharomyces cerevisiae metabolite na metabolite yimbeba.Ni enantiomer ya D-citrulline.Ni tautomer ya L-citrulline zwitterion.
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Chrysin CAS: 480-40-0 Utanga ibicuruzwa
Chrysin ni flavonoide isanzwe ifite antioxydants, anti-inflammatory, na anticancer.Ihagarika imvugo ya COX-2, umusaruro wa PGE2, hamwe na hydroxyl radical radical muri LPS iterwa na RAW 264.7.Chrysin ibuza imvugo ya HIF-1α iterwa na insuline (~ 50% kuri 10 μM) muri kanseri ya prostate yumuntu DU145 ikabuza DU145 xenograft iterwa na angiogenezi muri vivo.Muburyo bwimbeba yimvune ya ischemia / reperfusion, chrysin yagabanije imvugo ya gene-inflammatory na stress ya okiside, bigatuma igabanuka rya infarct nubusembwa bwa neurologiya.
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Itraconazole CAS: 84625-61-6 Utanga ibicuruzwa
Itraconazole ni clotrimazole yububiko bwa artificiel, kuba antifungal antifungal yagutse.Imiti igabanya ubukana hamwe na mikorobe ya mikorobe isa na clotrimazole, ariko ifite ibikorwa bikomeye bya antibacterial kurwanya Aspergillus.Ikoresha imbaraga zayo zo kurwanya ibihumyo binyuze muguhindura ingirabuzimafatizo ya selile ya fungal hamwe nibikorwa bya antibacterial kurwanya indwara ziterwa na virusi.Antibacterial spécran yayo ni nini kandi ikomeye kuruta ketoconazole, ibasha guhagarika synthesis ya ergosterol ya selile ya fungal selile, bityo ikagira ingaruka za antifungal.
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Piracetam CAS: 7491-74-9 Utanga ibicuruzwa
Piracetam ni urugingo rwa organonitrogene hamwe nuruvange rwa organooxyde.Ifitanye isano na acide alpha-amino.Ni uruganda rusabwa kuba nootropique ndetse na neuroprotective agent.Piracetam numuti wa nootropique ufite ibimenyetso byerekana ko ari imiti ivura myoclonus ikomoka kuri cortical, ndetse na dyskinesia ya tardive.
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Pyrroloquinoline Quinone Disodium Umunyu CAS: 122628-50-6
Pyrroloquinoline quinone disodium umunyu ni uruganda rukora amazi ya quinone rufite imbaraga za antioxydeant.Iki gicuruzwa nifu yumutuku wijimye.Yitandukanije n’umuco wa bagiteri methylotrophique na tissue yinyamabere.Iyi ntungamubiri yingenzi ningirakamaro ku nyamaswa z’inyamabere, zigira uruhare runini mu kongera imikorere y’umubiri.
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Cysteine CAS: 52-90-4 Utanga ibicuruzwa
L-Cysteine ni imwe muri 20 za aside amine karemano kandi, usibye methionine, imwe yonyine irimo sulfure.Ni thiol irimo aside amine idakenewe ya okiside kugirango ikore Cystine.Nibintu bidakenewe cyane birimo sulfure irimo aside amine mu bantu, ifitanye isano na cystine, Cysteine ni ingenzi mu gusanisha poroteyine, kwangiza, n'imikorere itandukanye ya metabolike.Cysteine iboneka muri beta-keratin, poroteyine nyamukuru mu nzara, ku ruhu, no ku musatsi, Cysteine ni ingenzi mu musaruro wa kolagen, ndetse no kuba uruhu rworoshye ndetse n’imiterere.
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Olmesartan CAS: 144689-24-7 Utanga ibicuruzwa
Olmesartan medoxomil, phenyl] phenyl] methyl] imidazole-4-carboxylate (Benicar, Olmetec) ikoresha sisitemu ya tetrazolering nka sisitemu ya aside irike, igira uruhare mu guhuza imiti. mugihe cyo kwinjizwa na gastrointestinaltract.Olmesartan ni biphenylyltetrazole.Ifite uruhare nka antivypertensive agent na angiotensin reseptor antagonist.
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Tirzepatide CAS: 2023788-19-2 Utanga ibicuruzwa
Tirzepatide yatejwe imbere nka agonisti ebyiri kuri GLP-1 hamwe na gastric inhibitory polypeptide (GIP) yakira (Frias et al., 2018).Kimwe na GLP-1, GIP ni imisemburo ya incretin ikora mu gutera insuline. .Irimo kwigwa kandi nk'ubuvuzi bushobora kuvura indwara ya steatohepatite idafite inzoga (NASH) no kunanirwa k'umutima hamwe n'uduce duto two gusohora (HFpEF).
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Aspartic Acide CAS: 56-84-8 Utanga ibicuruzwa
Acide ya Asparticikoreshwa nkinyongera yimirire, irashobora kuvangwa namabuye y'agaciro kugirango ikore ibice nka potasiyumu aspartate, umuringa wumuringa, manganese aspartate, magnesium aspartate, zinc aspartate nibindi byinshi.Kongera kwinjiza, bityo rero ubushobozi bwo gukoresha, bwamabuye y'agaciro hifashishijwe kongeramo aspartate bitera inyungu zimwe mubuzima.Abakinnyi benshi bakoresha L-aspartic acide ishingiye kumyunyu ngugu kugirango bongere ubushobozi bwabo.Aside ya Aspartic na acide glutamic igira uruhare runini nka acide rusange muri enzyme yibikorwa bikora, kimwe no gukomeza gukomera hamwe na ionic imiterere ya poroteyine.
