Itraconazole CAS: 84625-61-6 Umukozi Ukora

Itraconazole ni umuti urwanya indwara wa triazole. Ikoreshwa mu gukumira enzymes zishingiye kuri cytochrome P-450 hamwe no gukora ergosterol. Yakoreshejwe mu kurwanya histoplasmosis, blastotomycosis, cryptococcal meningitis, na aspergillosis. Uburyo butandukanye bwayo bukoreshwa mu kwiga ubwoko bwa Candida mu ndwara ziterwa n’udukoko two mu bwoko bwa murine. Yakoreshejwe mu kwiga impinduka zikwirakwira mu mucosa wa forestomach mu mbeba ziterwa na diyabete ziterwa na alloxan. Mu kuvura indwara zikurikira ziterwa n’udukoko ku barwayi bafite ubudahangarwa bw’umubiri n’abadafite ubudahangarwa bw’umubiri: blastomycosis y’ibihaha n’iy’ibihaha, histoplasmosis, aspergillosis, na onychomycosis.