Hydrocortisone, 11β, 17,21-trihydroxypregn-4-ene-3,20-dione, ni abantu ba mbere ba GCin karemano.Nubwo umubare munini wa GC yubukorikori, hydrocortisone, est est, hamwe nu munyu wacyo bikomeza kuba intandaro yubuvuzi bwa kijyambere bwa adrenocortical steroid hamwe nuburinganire bwo kugereranya izindi GC zose na MC.Irakoreshwa kubimenyetso byose byavuzwe mbere.