Inyigo iheruka ya Vitamine K2 MK7

Vitamine K2 MK7 (Menaquinone-7) ni ubwoko bw'ingenzi kandi bukora ku buzima bwa Vitamine K2, yitabwaho cyane kubera uruhare rwayo mu buzima bw'umutima n'amagufwa. Dore isesengura rirambuye.

· Itandukaniro ry'ibinyabutabire: Vitamine K2 ni imwe mu zigize umuryango wa menaquinone (MK), irangwa n'uruhererekane rw'ibice bya prenyl bisubiramo. MK7 ifite by'umwihariko ibi bice 7 bya isoprenoid ("MK" isobanura Menaquinone, "7″ bivuze uburebure bw'uruhererekane).

· Amasoko karemano:

· Ibiribwa Birimo Umusemburo: Inkomoko y'ibiribwa ikungahaye cyane ni natto (ibiryo gakondo by'Abayapani bikozwe muri soya zirimo umusemburo). Ibindi biribwa birimo umusemburo nka foromaje zimwe na zimwe (urugero: Gouda, Brie) na sauerkraut bikubiyemo ingano nto kandi ihinduka.

· Inkomoko y'amatungo: Iboneka ku gipimo gito mu muhondo w'igi, umwijima, n'inyama zirimo ibinure zikomoka ku nyamaswa zokejwe n'ibyatsi.

· Inyongeramusaruro: Iboneka cyane nk'inyongeramusaruro, akenshi ikomoka kuri natto fermentation cyangwa ikorwa mu buryo bw'ubukorano. Akenshi ihuzwa na Vitamine D3 na calcium kugira ngo ikoreshwe mu buryo bw'imikoranire.

Iki ni cyo gitekerezo cy'ingenzi gitandukanya Vitamine K2 (cyane cyane MK7):

· Ikora Poroteyine ya Matrix Gla (MGP): MGP ni umuti ukomeye ubuza imitsi gukaraba. Ifatana na iyoni za kalisiyumu mu nkuta z'imitsi y'amaraso kandi ikayibuza kwinjira mu tunyangingo tworoshye (imitsi, impyiko). MK7 ikora MGP. Iyo K2 idafite ihagije, MGP ikomeza gukora, bikongera ibyago byo gukomera kw'imitsi n'indwara z'umutima.

· Ikora Osteocalcin: Osteocalcin ni poroteyine ikorwa na osteoblasts (uturemangingo twubaka amagufwa). Inshingano yayo ni uguhuza kalisiyumu no kuyishyira mu gice cy'amagufwa, igakomeza amagufwa. MK7 ikora osteocalcin.

· Igereranya rya "Directeur wa Calcium": Tekereza Vitamine D nk'"umurinzi" utuma kalisiyumu ihagije yinjizwa mu mara igana mu maraso. Vitamine K2 (MK7) ikora nk'"umuyobozi w'imodoka" cyangwa "shuttle," igenzura ko kalisiyumu yinjizwa mu magufwa (binyuze muri osteocalcin) kandi ikagenzurwa n'imitsi (binyuze muri MGP).

1. Ubuzima bw'umutima n'imitsi:

· Bigabanya Gukomera kw'Imitsi no Gutera Kalisiyumu: Inyigo nyinshi zo kwitegereza no gukora ubushakashatsi zihuza uburyo bwinshi bwo gufata K2 (MK7) hamwe no kugabanya ibyago byo kurwara indwara z'umutima, gutera kalisiyumu mu mitsi, no gupfa. Inyigo ya ROTTERDAM ni inyigo izwi cyane yerekana iyi nyungu.

· Binoza uburyo bworoshye bwo gufungana: Kongera (urugero, 180-360 µg / ku munsi mu gihe cy'imyaka myinshi) byagaragaye ko byongera ubushobozi bwo koroshya imitsi.

2. Ubuzima bw'amagufwa:

· Igabanya ibyago byo kuvunika: Cyane cyane abagore bamaze gucura. K2 ikorana na Vitamine D na kalisiyumu kugira ngo yongere ubucucike bw'imyunyungugu mu magufwa (BMD) kandi igabanye ibyago byo kuvunika mu magufwa (mu mugongo no mu kibuno).

· Irinda Osteoporosis: Mu gukora osteocalcin byuzuye, ifasha mu kuvugurura amagufwa, bigatuma amagufwa aremwa kurusha kuyakoresha.

3. Izindi porogaramu zishobora gukoreshwa (Ubushakashatsi Bushya):

· Kumenya insuline neza na diyabete: Osteocalcin, iyo ikoreshejwe na K2, ishobora kugira uruhare mu kunoza uburyo insuline ifatwa neza.

· Ubuzima bw'Impyiko: Bishobora gufasha mu gukumira kolisiyumu y'imitsi ku barwayi barwaye indwara zidakira z'impyiko (CKD), nubwo gukoreshwa muri CKD bisaba ubugenzuzi bwa muganga bitewe n'ingorane zishobora kubaho.

· Ubuzima bw'amenyo: Kimwe n'amagufwa, bishobora gufasha amenyo kwiyungurura binyuze muri osteocalcin.

· Ubuzima bwo mu mutwe: Ubushakashatsi bw'ibanze bumwe buhuza ubuzima bw'imitsi (bushyigikiwe na K2) n'ibyago byo kugabanuka k'ubushobozi bwo mu mutwe.

Ikiranga Vitamine K2 MK7 Vitamine K2 MK4

Ikomoka ahanini ku guhinga bagiteri (natto). Iboneka mu bikomoka ku matungo; inyongeramusaruro nyinshi ni iz’ubukorano.

Igihe cy'igice cy'ubuzima (~amasaha 72). Itanga urugero ruhoraho mu maraso kuva ku gipimo kimwe. Gito (~amasaha 1-2). Isaba ko ihabwa kenshi (kenshi inshuro nyinshi ku munsi).

Kubaho neza ni byiza cyane; igihe kirekire cyo kubaho kwabyo gituma urugero rw'amaraso mu maraso rurushaho kuba rwinshi kandi rudahindagurika. Gusohora neza ariko vuba bigabanya ubwiyongere bw'ingingo.

Igipimo gisanzwe cya 90-360 µg/umunsi ni cyo gikunze gukoreshwa mu kongeramo imiti. Akenshi gikoreshwa mu bipimo by'imiti (1.5-45 mg/umunsi) mu bushakashatsi bwakorewe ku buvuzi.

Ikoreshwa ry'ibanze: Ubuzima bw'igihe kirekire bwo kwirinda amagufwa n'imitsi (inyongeramusaruro ku mirire). Umuti wanditswe na muganga (mu Buyapani) wo kurwanya indwara ya osteoporosis no kubura amagufwa bitewe na steroid.

Ibimenyetso Amakuru akomeye ku igeragezwa ry’indwara z’imitsi n’imitsi ajyanye n’inyungu z’umutima n’imitsi. Amakuru akomeye ku igeragezwa ry’igerageza ry’ibizamini ku nyungu z’amagufwa ku gipimo kiri hejuru kandi cy’imiti.

Umwanzuro: Muri rusange MK7 ikundwa cyane mu kongeramo imiti buri munsi bitewe n’uko ifite ubushobozi bwo gukora imiti (igihe kirekire cyo kubaho), bigatuma ikoreshwa rimwe ku munsi kandi ikagira uruhare ruhoraho mu gukora poroteyine zishingiye kuri K.

· Igipimo cy’inyongera gisanzwe: Gituruka kuri mikorogarama 90 (µg) kugeza kuri 360 µg ku munsi. Ubushakashatsi bwinshi ku byiza by’umutima n’imitsi bukoresha hafi 180-200 µg ku munsi.

· Umutekano: Ni umutekano ukomeye ku bipimo byasabwe abaturage muri rusange. Nta rwego rw'uburozi ruzwi rwagaragajwe.

· Ikoranabuhanga Rikomeye – Imiti igabanya amaraso mu mubiri (Warfarin/Coumadin):

· Vitamine K irwanya ingaruka za Warfarin. Abarwayi bafata Warfarin bagomba gufata Vitamine K buri gihe (ikomoka ku mirire n'inyongeramusaruro) kugira ngo ingano y'imiti yabo ikomeze kuba ihamye.

· NTIBAGOMBA gutangira cyangwa guhagarika imiti igabanya ubukana bwa K2 batabanje gukurikiranwa na muganga kandi bagakomeza gukurikiranwa kenshi na INR. Imiti mishya igabanya ubukana bw'amaraso (DOAC nka apixaban, rivaroxaban) ntigira ingaruka kuri Vitamine K.

· Guhuza: Buri gihe ufata hamwe na Vitamine D3. Ni ihuriro rikomeye ry’ibikorwa byo guhuza. Kalisiyumu na manyeziyumu nabyo ni intungamubiri z'ingenzi.

· Imiterere: Ibinini byoroshye cyangwa ibinini bifite amavuta (urugero: amavuta ya elayo, amavuta ya MCT) ni byiza cyane, kuko Vitamine K2 ishongesha mu mavuta.

· Formula zivanze: Shaka ibicuruzwa bivanze K2 (MK7) + D3. Kongeramo Vitamine K1 nke nabyo bishobora kugira akamaro kuri K-status yuzuye.

· Ubwiza: Hitamo ibirango bikoresha MK7 yose (uburyo ikora ku mubiri; bimwe mu bicuruzwa by’ubukorikori bishobora kuba birimo isomer idakora cyane).

· Kubika: Bika ahantu hakonje kandi hijimye. Bika neza mu nyongeramusaruro niba birinzwe urumuri n'ubushyuhe.

Muri make, Vitamine K2 MK7 ni intungamubiri y'ingenzi iyobora kalisiyumu mu magufwa mu gihe irinda imitsi n'uturemangingo tworoshye kwangirika. Imara igihe kirekire kimwe cya kabiri cy'ubuzima bwayo n'ibimenyetso bikomeye bigaragaza ko ari igice cy'ingenzi mu buryo bwo kwirinda indwara, cyane cyane ku buzima bw'umutima n'amagufwa, iyo ikoreshejwe hamwe na Vitamine D3.