Dithiothreitol (DTT), CAS: 3483-12-3, nk'igikoresho gikoreshwa cyane mu bushakashatsi bwa siyansi, gikunze gukoreshwa nk'ikintu kigabanya ADN ya sulfhydryl, ikintu kigabanya uburinzi, no kugabanya imigozi ya disulfide muri poroteyine. Ubwoko bushya bw'icyatsi kibisi bugira uruhare runini mu kunoza imikorere ya bateri.
Dithiothreitol (DTT) ni ikintu gikomeye cyo kugabanya, kandi kugabanuka kwayo biterwa ahanini n’uko impeta y’ingingo esheshatu (irimo imigozi ya disulfide) ihagaze neza mu gihe cyo kugabanya. Kugabanuka k’umugozi usanzwe wa disulfide na dithiothreitol bigizwe n’ibisubizo bibiri bikurikirana bya sulfhydryl-disulfide bond exchange reactions. Imbaraga zo kugabanya za dithiothreitol (DTT) zigira ingaruka ku gaciro ka pH, kandi zishobora kugira ingaruka ku kugabanuka gusa iyo agaciro ka pH karenze 7. Ibi biterwa nuko anions za thiolate za deprotonated gusa arizo zikora reactive, mu gihe mercaptans zitabikora, kandi pKa y’amatsinda ya mercapto muri rusange ni 8.3.
Dithiothreitol (DTT) ikoreshwa cyane mu kugabanya imigozi ya disulfide ya molekile za poroteyine na polypeptides. Ubusanzwe ikoreshwa nk'umuti urinda poroteyine sulfhydryl kandi ikoreshwa mu gutegura urukingo kugira ngo ikumire ibisigazwa bya poroteyine cysteine gukora disulfides zo mu nda ya molekyuli n'iziri hagati ya molekyuli. Mu gikorwa cyo gupima aside nucleic, dithiothreitol (DTT) ishobora gusenya imigozi ya disulfide muri poroteyine ya RNase, igahindura RNase, kandi yorohereza igeragezwa nko kubaka isomero rya RNA no kongera RNA. Dithiothreitol (DTT) ikoreshwa kandi nk'umuti wo kurinda uturemangingo n'uturemangingo, nk'umurinzi w'imirasire, nibindi.
Ariko, dithiothreitol (DTT) akenshi ntishobora kugabanya imigozi ya disulfide iri mu miterere ya poroteyine (idashobora kugerwaho n'ibintu biyungurura). Kugabanya imigozi nk'iyo ya disulfide akenshi bisaba ko poroteyine ibanza guhindagurika.
Kugira ngo uhagarike ingaruka za bateri za lithiamu-sulfure kandi wongere imikorere ya electrochemical ya bateri za lithiamu-sulfure, gerageza gukoresha dithiothreitol (DTT) nk'igikoresho cyo gukata polysulfide zo mu rwego rwo hejuru kugira ngo zibuze gushonga. Threitol (DTT) ivangwa mu mpapuro za nanotubes za karuboni nyinshi (MWCNTs) kugira ngo utegure interlayer ya DTT. Interlayer ya DTT ishyirwa hagati y'urupapuro rwa electrode nziza n'agace gatandukanya buto ya lithiamu-sulfure igice cy'uturemangingo, n'ubuso bw'urupapuro rwa electrode nziza butwara sulfur hafi 2mg/cm2. Ibisubizo bya SEM byemeza ko DTT ikwirakwijwe neza ku buso n'imyanda by'urupapuro rwa MWCNTs. Ibisubizo by'ibizamini bya electrochemical bigaragaza ko bateri ya lithiamu-sulfure ifite imiterere ya sandwich ya DTT ifite ubushobozi bwo gusohora bwa mbere bwa 1288 mAh/g ku gipimo cya 0.05C. Ku nshuro ya mbere, ubushobozi bwa coulombic buri hafi 100%, kandi ubushobozi bwihariye mu gihe cyo gushyushya no gusohora kuri 0.5C, 2C, na 4C bugera kuri 650mAh/g, 600mAh/g, na 410mAh/g, uko bikurikirana. Kwinjizwa kwa sandwich ya DTT bishobora gukata neza polysulfides zo mu rwego rwo hejuru. Biyirinda kwimukira kuri electrode ya lithium negative, bityo bikabuza shuttle effect no kunoza cycle stability na coulomb efficiency ya bateri za lithium-sulfur.
Ni ngombwa kumenya ko dithiothreitol (DTT) ari ikintu cy’uburozi. Urugero, iyo hari ibyuma bihinduka, dithiothreitol (DTT) ishobora kwangiza ogisijeni ku ngirabuzimafatizo z’ibinyabuzima. Muri icyo gihe, dithiothreitol (DTT) ishobora no kongera uburozi bw’ibintu bimwe na bimwe birimo arsenic na mercure. Dithiothreitol (DTT) ifite impumuro mbi, ishobora kwangiza ubuzima bitewe no guhumeka no gukora ku ruhu. Kubwibyo, ni ngombwa kuyirinda mu gihe cyo kuyikoresha, kwambara udupfukamunwa, uturindantoki n’amadarubindi, no kuyikorera mu gipfundikizo cy’umuriro.
Thithreitol (DTT) nk'ikintu gifasha mu gukata bateri za lithiamu-sulfure
Bateri ya Lithium-sulfure ifatwa nk'uburyo bwa bateri bufite ubushobozi bwinshi bitewe n'ubucucike bwayo buhanitse bw'ingufu no kurengera ibidukikije. Ariko, "ingaruka za shuttle" za polysulfides zituma ubuzima bw'uruziga budakora neza kandi zigasohora amazi mu buryo bukomeye, ibyo bigatuma idashobora gukoreshwa neza.
Thiothreitol (DTT) ishobora kongerwa muri batiri nk'ikintu gifasha gukata. Ishobora gukata vuba imigozi ya disulfide ku bushyuhe bw'icyumba, gukata polysulfide zo mu rwego rwo hejuru kugira ngo hirindwe ko zishonga, kubuza ubwikorezi bw'imodoka, no kongera imikorere ya litiyumu ya batiri za sulfur.
Dithiothreitol (DTT) nk'inyongera ya electrolyte muri batiri za aluminiyumu/umwuka za alkaline
Muri batiri za aluminiyumu/umwuka za alkaline, dithiothreitol ishobora gukora urwego rumwe kandi ruhamye rwo kurinda binyuze mu migozi ihindagurika ku buso bwa anode ya aluminiyumu, ikabuza iyo anode ya aluminiyumu kwiyangiza, kandi ikanoza neza imikorere yayo.
Igihe cyo kohereza: Ukuboza 31-2021