Acetyl Octapeptide-3 CAS: 868844-74-0 uburyo bwo kuyikoresha no kuyikoresha

Acetyl Octapeptide-3 (CAS 868844-74-0) ni peptide izwi cyane mu buhanga bwo kwisiga, ikunze kugurishwa ku izina ry'ubucuruzi rya SNAP-8. Reka turebere hamwe uburyo ikoreshwa n'uburyo ikoreshwa mu buryo burambuye.

1. Umwirondoro n'uburyo bwo gukora

· Indangamuntu y'ibinyabutabire:Ni peptide ya acetylated synthetic ifite urukurikirane rwa Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2. Acetylation yongera kwinjira no guhagarara k'uruhu.

· Uburyo bw'ibanze:Akenshi yitwa "uburyo bwo guhindura Botox mu mubiri," imikorere yayo ishingiye ku gukumira gupiganwa. Imera nk'igice cya N-terminal cya poroteyine ya SNAP-25, igice cy'ingenzi muri SNARE complex gikenewe kugira ngo imitsi irekure (nka acetylcholine) igaragaza ko imitsi ikora neza.

· Ingaruka z'ingenzi:Mu guhangana na SNAP-25 karemano kugira ngo igire umwanya muri SNARE complex, bibuza ikorwa ry’urusobe rw’imikorere yuzuye. Ibi bituma habaho kugabanuka gato kw’irekurwa ry’imitsi ya neurotransmitter, bigatera kugabanuka k’ubukana n’inshuro zo gupfunyika kw’imitsi yo mu maso, bityo bigatuma imirongo igaragara, cyane cyane ku gahanga no hafi y’amaso irushaho kumera neza.

2. Amabwiriza agenga itegurwa

Acetyl Octapeptide-3 ni ikintu gikomeye ariko cyoroshye. Uburyo bwiza bwo kuyitunganya ni ingenzi cyane kugira ngo ihamye kandi ikore neza.

A) Ibyifuzwa byo gushyiramo imbaraga:

· Urwego rusanzwe rwo gukoresha ruri hagati ya2% kugeza kuri 10%cy'umuti wa peptide wabanje gushonga.

· Ibikubiye muri peptide ikora mu bikoresho fatizo (akenshi ifu y'umweru ya lyophilized) akenshi biba ari ibintu bisanzwe. Abacuruza ibicuruzwa basanzwe bayitanga nk'umuti2% cyangwa 5%umuti washongeshejwe mbere (mu mazi cyangwa mu mvange y'amazi/glycerin) kugira ngo woroshye gukoresha.

· Ingano ya nyuma ya peptide ikora mu musaruro wa nyuma akenshi iba iri hagati ya0.0005% kugeza 0.002% (5-20 ppm)Buri gihe kurikiza amabwiriza y’ingano y’ibipimo by’umucuruzi wawe w’ibikoresho fatizo.

B) Gushonga no gushonga kw'imodoka:

· Ishonga cyane mu mazi. Iba nziza cyane mu gihe cy'amazi mu gicuruzwa.

· Imodoka zikwiriye zirimo:

· Seramu (zikunze kugaragara cyane)

· Gel

· Amavuta yo kwisiga n'amavuta yo kwisiga (agomba gushyirwa mu gice cy'amazi mbere yo kuyavanga)

· Amavuta yo kwisiga aturuka ku mazi

· Ibisubizo bishobora gusukwa

C) pH n'Uburimbane:

· Ingano nziza ya pH:5.0 – 7.0Gutunganya muri uru rwego bitanga ubushobozi bwo kugumana imiti ikoreshwa mu ruhu no guhuza uruhu.

· Irinde ahantu hafite aside nyinshi (pH < 4) cyangwa alkaline (pH > 8) mu gihe kirekire.

D) Ubushyuhe n'Itunganywa:

· Irinda ubushyuhe. Kugira ngo hirindwe kwangirika:

· Shyiramo amazi mu gice cyangwa munsi yayoUbushyuhe bwa 40°C (104°F).

· Aho gukonjesha neza ni nyuma yuko emulsion ikonje kugeza munsi ya 40°C, cyangwa kuyishongesha mu mazi y'ubushyuhe bw'icyumba kugira ngo ukoreshe serum/gels.

· Irinde gutunganya ubushyuhe bwinshi nko kuzuza ibintu bishyushye keretse amakuru y’ubudahangarwa abyemeza.

E) Ibikoresho bihuye n'ibikenewe:

· Ifite: Izindi peptide zirwanya gusaza (urugero: Matrixyl, Argireline), aside hyaluronic, niacinamide, antioxydants (Vitamine C na E), moisturizers.

· Uruvange rw'ibikorwa bihuriweho:

· Ku zindi peptides zihindura imikorere y'ubwonko: Akenshi zihuzwa na Acetyl Hexapeptide-8 (Argireline) kugira ngo zigire ingaruka nziza kandi zigabanya ingaruka nyinshi.

· Hamwe na peptides zitera imbaraga za kolajeni: Guhuza na peptides nka Palmitoyl Tripeptide-1 cyangwa Matrixyl bikemura ibibazo byombi ku miterere ihindagurika (ituruka ku mikorere y'imitsi) ndetse no ku miterere idahinduka (ituruka ku gutakaza inkunga y'imiterere).

· Irinde: Ibintu bigabanya cyangwa bigabanya ubwinshi bw'ibintu bihumanya ikirere. Witondere ibintu bimwe na bimwe bya iyoni bishobora kugira ingaruka ku gushonga kwabyo cyangwa ku miterere yabyo.

F) Kubungabunga:

· Nk'ikintu gishongesha mu mazi, ikoreshwa rya nyuma risaba uburyo bukomeye bwo kubungabunga ibidukikije kugira ngo hirindwe ko mikorobe zishobora kwangiza peptide.