Natamycin/Pimaricin CAS: 7681-93-8 Umukozi Ukora

Pimaricin ni ubwoko bwa macrocyclic tetraene bwakuwe muri Streptomyces natalensis mu 1957. Pimaricin igaragaza imikorere yagutse yo kurwanya umusemburo n'ibihumyo byuzuyemo uduce duto, ifatanya na ergosterol kugira ngo ihagarike gukura kw'ibihumyo. Bitandukanye na polyenes zifitanye isano, nystatin na filipine, pimaricin ntabwo ihindura uburyo plasma membrane inyuramo. Pimaricin ikoreshwa mu nganda z'ibiribwa mu kuvura foromaje hejuru nk'umuti ubuza imyuka. Natamycin ni antibiyotike ya polyene ikoze mu buryo buciriritse. Natamycin ntishonga neza mu mazi kandi ntishobora kwinjira mu gice cy'inyuma cy'ijisho. Natamycin ni yo miti yonyine irwanya imyuka yemerewe gukoreshwa ku jisho kandi ni wo muti rukumbi uboneka ku isoko mu kuvura keratite y'ibihumyo. Natamycin, izwi kandi ku izina rya pimaracin, iri mu muryango wa polyene wa antibiyotike; (itsinda ry'imiti irwanya imyuka yibasira kandi ifatanya na sterol zo mu bwoko bwa eukaryotic cyane cyane ergosterol), kandi ni metabolite ya kabiri ya Streptomyces natalensis.