N-Acetyl-D-phenylalanine CAS: 10172-89-1

N-Acetyl-D-phenylalanine ifite akamaro gakomeye muri shimi ya peptide nk'igice cy'ingenzi mu gukora peptide na peptidomimetics. Nk'ikivange cya D-phenylalanine cya acetyl, ikora nk'igikoresho cyo kwinjiza ibisigazwa bya chiral byihariye mu minyururu ya peptide binyuze mu buryo bwo gukora peptide y'igice gikomeye n'icyiciro cy'umuti. Abashakashatsi n'abahanga mu bya shimi bakoresha N-Acetyl-D-phenylalanine kugira ngo bahindure uruhererekane rwa peptide hamwe n'igenzura ryimbitse rya stereochemical, bigatuma hakorwa imiterere mishya ya bioactive na peptides zo kuvura zigamije kwakira, enzymes, cyangwa transporters muri sisitemu y'ibinyabuzima. Byongeye kandi, N-Acetyl-D-phenylalanine ikoreshwa nk'inkingi y'ubwubatsi bwa chiral mu gukora imiti ihuza imiti, aho stereochemistry yayo yihariye ari ingenzi mu gukora imiti ya chiral n'ibiyigize bihuza bioactive. Chiralité yayo n'ubudahangarwa bwayo bituma iba ingenzi mu gukora imiti, yongera imiterere ya farumasi n'imikorere ya biyolojiya y'imiti ya nyuma. Byongeye kandi, N-Acetyl-D-phenylalanine ikoreshwa mu bushakashatsi bwa biochemical kugira ngo yige metabolism ya phenylalanine, imikorere ya poroteyine, na kinetics ya enzyme. Uruhare rwayo mu gusobanura inzira z'uturemangingo n'imikorere ya metabolic bigira uruhare mu gusobanukirwa imikorere ya phenylalanine mu buryo bw'ibinyabuzima n'ingaruka zishobora kugira ku buzima n'indwara. Muri make, N-Acetyl-D-phenylalanine igira uruhare runini mu guteza imbere ubushakashatsi bwa siyansi, iterambere ry'imiti, n'ubushakashatsi ku binyabuzima, iha abahanga mu bya siyansi n'inzobere igikoresho gikoreshwa mu gusesengura ikoreshwa ry'ibintu bikomoka kuri phenylalanine mu kuvumbura imiti, gukora peptide, no gukora ubushakashatsi ku binyabuzima.