Ibandronate Sodium CAS: 138844-81-2 Umukozi Ukora

Ibandronate sodium yakoreshejwe mu kwiga ingaruka zayo ku kwiyongera no ku miterere ya Leishmania na Giardia binyuze mu gukora ingero z’ibipimo. Yanakoreshejwe mu gusobanura inzira bisphosphonates (N-BPs) zirimo azote zinjira muri cytosol zikabuza intego yazo ya molekile. Ibandronate sodium ibuza farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium nayo ni inzitizi yo kugabanya amagufwa. Yakoreweho ubushakashatsi ku ngaruka zo kurwanya kanseri mu buryo bwa vitro, nko gutera apoptosis, gukumira gukura kw'uturemangingo, gukumira imyitwarire yo kwangiza, no gukumira angiogenesis ndetse no ku ruhare rwayo mu mubiri muri kanseri zitandukanye harimo na kanseri y'ibere na prostate.