Hemin = Chlorohemin CAS:16009-13-5 Igiciro cy'umukozi

Gutwara ogisijeni: Hemin ni igice cy'ingenzi cya hemoglobine, ituma uturemangingo dutukura tw'amaraso dushobora gufata no gutwara ogisijeni mu ngingo z'umubiri wose. Ibi bituma ogisijeni ikwirakwira neza kandi bigafasha ihumeka ry'uturemangingo.

Ikorwa rya Heme: Hemin igira uruhare mu ikorwa rya heme, molekile y'ingenzi mu mikorere ya hemoproteine ​​zitandukanye. Izi zirimo myoglobin, cytochromes, na catalases, zigira uruhare runini mu kubika ogisijeni, gutwara electron, no gukora imisemburo y'uturemangingo.

Imikorere ya Coenzyme: Hemin ikora nk'itsinda rya coenzyme rikora imisemburo myinshi igira uruhare mu mikorere ya heme na bilirubin. Ikora nk'itsinda rituma habaho imikorere ya enzyme, bigatuma heme na bilirubin bitunganywa neza kandi bigakurwaho mu mubiri.

Kugenzura igaragara ry’uturemangingo: Hemin ifite ubushobozi bwo kugenzura igaragara ry’uturemangingo binyuze mu gukorana n’uturemangingo twa ADN, tuzwi nka promoters, no kugira ingaruka ku ihindurwa ry’uturemangingo tw’ingenzi. Iyi miterere yakoreshejwe mu bushakashatsi bwa laboratwari mu kwiga ingaruka za hemin ku nzira runaka z’uturemangingo n’imigendekere y’indwara.

Kuvura Porphyria: Ubuvuzi bwa Hemin bukoreshwa mu kuvura porphyria, itsinda ry'indwara za genetike zirangwa n'ubusembwa mu gukora heme. Mu gutanga hemine yo hanze, bifasha kugarura urugero rwa heme rukwiye, bikagabanya ibimenyetso no gukumira ibitero bikomeye biterwa no kwirundanya kw'ibintu bihumanya bya heme.