H-His-OMe·2HCl CAS: 7389-87-9

H-His-OMe·2HCl ikora nk'ingenzi mu kubaka peptide, igira uruhare runini mu kubaka peptide zifite imiterere yihariye n'imikorere. Kuba hari itsinda rya methyl ester n'umunyu wa hydrochloride bituma ibisigazwa bya histidine biguma bidahinduka mu gihe cyo gukora peptide, bigatuma peptide iteranywa neza kandi igenzurwa. Iki kintu gifite akamaro mu gushushanya peptide zifite imiterere yihariye nko kunoza ubusugire, gushonga, cyangwa kuba bioavailability, bigatuma kiba igikoresho cy'ingenzi mu iterambere ry'imiti, cyane cyane mu gukora imiti ishingiye kuri peptide ifite ubushobozi bwo kuvura burushijeho kwiyongera bitewe n'imiterere y'umunyu. Uretse uruhare rwayo mu gukora peptide, H-His-OMe·2HCl ikoreshwa mu bushakashatsi bwa poroteyine n'ubuhanga bwa biochemical, aho ishobora gukoreshwa mu kwiga imikoranire ya poroteyine na poroteyine, gukora ubushakashatsi ku bikorwa bya enzyme, no gusuzuma imikorere ya poroteyine. Imiterere yayo ijyanye n'imiterere ye ituma abashakashatsi bashobora gusuzuma uburyohe bw'imikorere y'uturemangingo n'uburyo indwara zigenda, bigira uruhare mu iterambere mu gusobanukirwa ubuzima n'indwara. Uburyo iyi mvange ikora neza kandi ihuye n’imiterere itandukanye y’igerageza bituma iba ingenzi cyane mu gusesengura ingorane z’imikorere y’ibinyabuzima no guteza imbere uburyo bwo kuvura indwara zitandukanye. Muri make, H-His-OMe·2HCl ni igikoresho cy’agaciro ku bashakashatsi mu bijyanye no gukora peptide, guteza imbere imiti, n’ubushakashatsi ku binyabuzima, itanga ubushobozi bwo guhindura peptide zifite imiterere yihariye no gusesengura uburyo bw’ibanze bw’imikorere y’ibinyabuzima, bityo ikagira uruhare mu iterambere mu buvuzi no mu ikoranabuhanga.