Fmoc-His(Fmoc)-OH CAS:98929-98-7

Fmoc-His (Fmoc)-OH ikoreshwa cyane mu buvuzi bwa peptide, bioconjugation, n'ubushakashatsi mu by'imiti kugira ngo hakorwe peptide zikungahaye kuri histidine zifite imiterere n'ibikorwa byihariye. Nk'igice cy'ingenzi mu gukora peptide ikomeye, ituma habaho peptide zo kwiga uburyo ibyuma bihambira, catalysis ya enzyme, n'imikoranire ya receptor na ligand. Abashakashatsi bakoresha Fmoc-His (Fmoc)-OH kugira ngo bakore peptide zo kuvura, nko kwibanda ku bice bya poroteyine zikungahaye kuri histidine bigira uruhare mu ndwara cyangwa nk'abahindura imiterere y'imiti ishingiye ku byuma. Ubuziranenge bwinshi n'uburinzi bubiri bwa Fmoc-His (Fmoc)-OH bituma iba amahitamo meza yo gukora peptide zifite ububasha bwo kugenzura neza aho histidine iherereye n'uburyo ikora. Ihuye n'uburyo busanzwe bwo gukora peptide n'amabwiriza bitanga icyizere cyo kwihuza neza mu mikorere ya laboratwari, bigatuma abahanga mu bya siyansi bashobora gukora peptide zikungahaye kuri histidine zijyanye n'ibyo bakeneye mu bushakashatsi. Byaba bikoreshwa mu mashuri makuru cyangwa mu nganda, Fmoc-His (Fmoc)-OH igira uruhare mu guteza imbere ubushakashatsi bushingiye kuri peptide, iterambere ry'imiti, no gusesengura uruhare rutandukanye rwa histidine mu mikorere y'ibinyabuzima no mu buvuzi.