Fmoc-Arg(Tos)-OH CAS:83792-47-6

Fmoc-Arg (Tos)-OH igira uruhare runini mu gukora peptide, cyane cyane iyo hakenewe kurinda neza azote ya guanidine muri arginine. Itsinda ririnda Fmoc rikingira itsinda rya amino, rigatanga ibisubizo byihariye mu gihe cyo guhuza peptide, mu gihe itsinda rya tosyl riri kuri azote ya guanidine ritanga ubundi buryo bwo kurinda. Abashakashatsi bakoresha Fmoc-Arg (Tos)-OH mu gukora peptide hifashishijwe guhindurirwa guanidine, bigira ingaruka ku bikorwa byazo bya biyoloji. Uburyo bwo kurinda bubiri butuma habaho uburyo bwo kugenzura uburyo guanidine ikora, bigatuma iki kintu kiba ingirakamaro mu gushushanya peptides mu bushakashatsi bwa antibiyotike, guhuza bioconjugation, no gukoresha imiti. Kuba Fmoc-Arg (Tos)-OH ihura n'uburyo busanzwe bwo gukora peptides, harimo no gukora peptides mu buryo bwa solid-phase (SPPS), byongera akamaro kabyo. Iki kintu gikoreshwa mu gukora peptides mu gusuzuma ibinyabuzima, kuvumbura imiti, no guteza imbere ibikoresho bishingiye kuri peptide. Gukuraho amatsinda yo kurinda bigenzurwa bituma arginine ishyirwa mu buryo bw’ingamba hamwe na guanidine yahinduwe, bigatera imbere mu budasa bwa peptide zishobora gukorwa. Muri make, Fmoc-Arg (Tos)-OH ni igikoresho cyihariye kandi gifite uburyo bwinshi mu bijyanye na peptide, giha abashakashatsi ubushobozi bwo gushakisha no guhindura uburyo guanidine ikora mu buryo butandukanye mu bya siyansi no mu buvuzi.