Fmoc-Arg(pbf)-OH CAS:154445-77-9

Fmoc-Arg(pbf)-OH ifite akamaro kanini mu gukora peptide, cyane cyane mu bihe bisaba uburinzi bugenzurwa bwa azote ya guanidine muri arginine. Itsinda ririnda Fmoc rikingira itsinda rya amino, rikorohereza ibikorwa byo guhitamo mu gihe cyo guhuza peptide, mu gihe itsinda rya pbf riri kuri azote ya guanidine ritanga ubundi buryo bwo kurinda. Abashakashatsi bakoresha Fmoc-Arg(pbf)-OH mu gukora peptide hamwe n'impinduka zihariye za guanidine, bigira ingaruka ku bikorwa byazo bya biyoloji. Ingamba zo kurinda ebyiri zituma habaho gukoresha neza guadinine reactivity, bigatuma iyi compound igira akamaro mu gushushanya no guteza imbere peptides mu bushakashatsi bwa antimicrobial, bioconjugation, na chemistry y'ubuvuzi. Kuba Fmoc-Arg(pbf)-OH ihuye n'uburyo busanzwe bwo gukora peptide, harimo no gukora peptide synthesis (SPPS), byongera akamaro kayo. Iyi compound ikoreshwa mu kubaka peptides mu gusuzuma ibinyabuzima, kuvumbura imiti, no guteza imbere ibikoresho bishingiye kuri peptide. Gukuraho amatsinda yo kurinda bigenzurwa bituma arginine ishyirwa mu buryo bw’ingufu hamwe na guanidine yahinduwe, bigatera imbere mu budasa bwa peptide zishobora gukorwa. Muri make, Fmoc-Arg (pbf)-OH ni igikoresho cyihariye kandi gifite uburyo bwinshi mu bijyanye na peptide chimie, giha abashakashatsi ububasha bwo gushakisha no guhindura uburyo guanidine ikora mu buryo butandukanye mu bya siyansi no mu buvuzi.